rs4837362

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0200 (5951/29748,GnomAD)
A==0214 (6252/29118,TOPMED)
A==0221 (1105/5008,1000G)
A==0234 (902/3854,ALSPAC)
A==0248 (920/3708,TWINSUK)
chr9:129400975 (GRCh38.p7) (9q34.11)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.129400975A>C
GRCh38.p7 chr 9NC_000009.12:g.129400975A>T
GRCh37.p13 chr 9NC_000009.11:g.132163254A>C
GRCh37.p13 chr 9NC_000009.11:g.132163254A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.181C=0.819
1000GenomesAmericanSub694A=0.230C=0.770
1000GenomesEast AsianSub1008A=0.170C=0.830
1000GenomesEuropeSub1006A=0.252C=0.748
1000GenomesGlobalStudy-wide5008A=0.221C=0.779
1000GenomesSouth AsianSub978A=0.290C=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.234C=0.766
The Genome Aggregation DatabaseAfricanSub8652A=0.179C=0.821
The Genome Aggregation DatabaseAmericanSub836A=0.170C=0.83,
The Genome Aggregation DatabaseEast AsianSub1610A=0.168C=0.832
The Genome Aggregation DatabaseEuropeSub18348A=0.213C=0.786
The Genome Aggregation DatabaseGlobalStudy-wide29748A=0.200C=0.799
The Genome Aggregation DatabaseOtherSub302A=0.270C=0.73,
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.214C=0.785
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.248C=0.752
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs48373620.00025alcohol dependence24277619

eQTL of rs4837362 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4837362 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr93033307930333191E06720497
chr93033332030333400E06720738
chr93036057030360610E06747988
chr93036082530360905E06748243
chr93033307930333191E06920497
chr93033332030333400E06920738
chr93033293230333000E07120350
chr93033307930333191E07120497
chr93033293230333000E07220350
chr93033307930333191E07220497
chr93036057030360610E07447988
chr93036082530360905E07448243