rs4841962

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0409 (12197/29812,GnomAD)
A==0354 (1773/5008,1000G)
A==0488 (1882/3854,ALSPAC)
A==0477 (1770/3708,TWINSUK)
chr9:135303357 (GRCh38.p7) (9q34.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.135303357A>C
GRCh38.p7 chr 9NC_000009.12:g.135303357A>T
GRCh37.p13 chr 9NC_000009.11:g.138195203A>C
GRCh37.p13 chr 9NC_000009.11:g.138195203A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.247C=0.753
1000GenomesAmericanSub694A=0.430C=0.570
1000GenomesEast AsianSub1008A=0.340C=0.660
1000GenomesEuropeSub1006A=0.431C=0.569
1000GenomesGlobalStudy-wide5008A=0.354C=0.646
1000GenomesSouth AsianSub978A=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.488C=0.512
The Genome Aggregation DatabaseAfricanSub8698A=0.263C=0.737
The Genome Aggregation DatabaseAmericanSub830A=0.440C=0.56,
The Genome Aggregation DatabaseEast AsianSub1546A=0.319C=0.681
The Genome Aggregation DatabaseEuropeSub18438A=0.485C=0.514
The Genome Aggregation DatabaseGlobalStudy-wide29812A=0.409C=0.590
The Genome Aggregation DatabaseOtherSub300A=0.340C=0.66,
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.477C=0.523
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs48419620.000867alcohol dependence24277619

eQTL of rs4841962 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4841962 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.