SNP Detail Info-rs4844438

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0016 (490/29984,GnomAD)
G=0015 (437/29116,TOPMED)
G=0069 (345/5008,1000G)
G=0003 (13/3854,ALSPAC)
G=0002 (9/3708,TWINSUK)

Position: chr1:208741511 (GRCh38.p7) (1q32.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 30 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.208741511A>G
GRCh37.p13 chr 1	NC_000001.10:g.208914856A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.999	G=0.001
1000Genomes	American	Sub	694	A=0.940	G=0.060
1000Genomes	East Asian	Sub	1008	A=0.810	G=0.190
1000Genomes	Europe	Sub	1006	A=0.998	G=0.002
1000Genomes	Global	Study-wide	5008	A=0.931	G=0.069
1000Genomes	South Asian	Sub	978	A=0.890	G=0.110
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.997	G=0.003
The Genome Aggregation Database	African	Sub	8728	A=0.998	G=0.002
The Genome Aggregation Database	American	Sub	838	A=0.930	G=0.070
The Genome Aggregation Database	East Asian	Sub	1612	A=0.795	G=0.205
The Genome Aggregation Database	Europe	Sub	18504	A=0.995	G=0.004
The Genome Aggregation Database	Global	Study-wide	29984	A=0.983	G=0.016
The Genome Aggregation Database	Other	Sub	302	A=1.000	G=0.000
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.985	G=0.015
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.998	G=0.002

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs4844438	0.00092	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	208905453	208906282	E070	-8574
chr1	208940264	208940406	E070	25408
chr1	208943847	208943930	E070	28991
chr1	208943952	208944052	E070	29096
chr1	208944146	208944351	E070	29290
chr1	208954921	208955077	E070	40065
chr1	208955112	208955280	E070	40256
chr1	208955289	208955690	E070	40433
chr1	208955714	208955808	E070	40858
chr1	208956122	208956213	E070	41266
chr1	208960719	208960861	E070	45863
chr1	208961387	208961806	E070	46531
chr1	208961850	208962043	E070	46994
chr1	208962101	208962151	E070	47245
chr1	208905453	208906282	E081	-8574
chr1	208910539	208910956	E081	-3900
chr1	208921092	208921168	E081	6236
chr1	208921906	208922565	E081	7050
chr1	208954921	208955077	E081	40065
chr1	208955112	208955280	E081	40256
chr1	208955714	208955808	E081	40858
chr1	208960719	208960861	E081	45863
chr1	208961387	208961806	E081	46531
chr1	208961850	208962043	E081	46994
chr1	208962101	208962151	E081	47245
chr1	208960719	208960861	E082	45863
chr1	208961387	208961806	E082	46531
chr1	208961850	208962043	E082	46994
chr1	208962101	208962151	E082	47245
chr1	208964262	208964330	E082	49406

rs4844438