rs4845133

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0135 (4056/29906,GnomAD)
G=0161 (4714/29118,TOPMED)
G=0118 (593/5008,1000G)
G=0100 (386/3854,ALSPAC)
G=0102 (377/3708,TWINSUK)
chr1:206741989 (GRCh38.p7) (1q32.1)
AD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
115 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.206741989C>G
GRCh37.p13 chr 1 fix patch HG1293_PATCHNW_003871057.1:g.732843C>G
GRCh37.p13 chr 1NC_000001.10:g.206915334C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.757G=0.243
1000GenomesAmericanSub694C=0.910G=0.090
1000GenomesEast AsianSub1008C=0.942G=0.058
1000GenomesEuropeSub1006C=0.888G=0.112
1000GenomesGlobalStudy-wide5008C=0.882G=0.118
1000GenomesSouth AsianSub978C=0.960G=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.900G=0.100
The Genome Aggregation DatabaseAfricanSub8690C=0.774G=0.226
The Genome Aggregation DatabaseAmericanSub836C=0.920G=0.080
The Genome Aggregation DatabaseEast AsianSub1618C=0.938G=0.062
The Genome Aggregation DatabaseEuropeSub18460C=0.897G=0.102
The Genome Aggregation DatabaseGlobalStudy-wide29906C=0.864G=0.135
The Genome Aggregation DatabaseOtherSub302C=0.870G=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.838G=0.161
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.898G=0.102
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs48451330.000911alcohol dependence21314694

eQTL of rs4845133 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4845133 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1752443752811E06719600
chr1761040761094E06728197
chr1761314761416E06728471
chr1761040761094E06828197
chr1761314761416E06828471
chr1752443752811E06919600
chr1754018754252E06921175
chr1754361754414E06921518
chr1754431754492E06921588
chr1752443752811E07119600
chr1753235753298E07120392
chr1753329753698E07120486
chr1753809753866E07120966
chr1754018754252E07121175
chr1754361754414E07121518
chr1758109758194E07125266
chr1761314761416E07128471
chr1753809753866E07220966
chr1754018754252E07221175
chr1754361754414E07221518
chr1754431754492E07221588
chr1753329753698E07320486
chr1752443752811E07419600
chr1753235753298E07420392
chr1761040761094E08128197
chr1761314761416E08128471
chr1761040761094E08228197
chr1761314761416E08228471









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1713612713675E067-19168
chr1713875714372E067-18471
chr1714448714670E067-18173
chr1714702714752E067-18091
chr1715081715151E067-17692
chr1715184715305E067-17538
chr1762058762232E06729215
chr1762272762339E06729429
chr1762426762534E06729583
chr1762544762618E06729701
chr1762648763017E06729805
chr1713612713675E068-19168
chr1713875714372E068-18471
chr1714448714670E068-18173
chr1714702714752E068-18091
chr1715081715151E068-17692
chr1715184715305E068-17538
chr1715374715438E068-17405
chr1762058762232E06829215
chr1762272762339E06829429
chr1762426762534E06829583
chr1762544762618E06829701
chr1762648763017E06829805
chr1763070763165E06830227
chr1713612713675E069-19168
chr1713875714372E069-18471
chr1714448714670E069-18173
chr1714702714752E069-18091
chr1715081715151E069-17692
chr1715184715305E069-17538
chr1762058762232E06929215
chr1762272762339E06929429
chr1762426762534E06929583
chr1762544762618E06929701
chr1762648763017E06929805
chr1763070763165E06930227
chr1713612713675E070-19168
chr1713875714372E070-18471
chr1714448714670E070-18173
chr1714702714752E070-18091
chr1715081715151E070-17692
chr1715184715305E070-17538
chr1762058762232E07029215
chr1762272762339E07029429
chr1762426762534E07029583
chr1762544762618E07029701
chr1762648763017E07029805
chr1763070763165E07030227
chr1763672763722E07030829
chr1713612713675E071-19168
chr1713875714372E071-18471
chr1714448714670E071-18173
chr1714702714752E071-18091
chr1715081715151E071-17692
chr1715184715305E071-17538
chr1762058762232E07129215
chr1762272762339E07129429
chr1762426762534E07129583
chr1762544762618E07129701
chr1762648763017E07129805
chr1763070763165E07130227
chr1713612713675E072-19168
chr1713875714372E072-18471
chr1714448714670E072-18173
chr1714702714752E072-18091
chr1715081715151E072-17692
chr1715184715305E072-17538
chr1715374715438E072-17405
chr1762058762232E07229215
chr1762272762339E07229429
chr1762426762534E07229583
chr1762544762618E07229701
chr1762648763017E07229805
chr1763070763165E07230227
chr1713612713675E073-19168
chr1713875714372E073-18471
chr1714448714670E073-18173
chr1714702714752E073-18091
chr1715081715151E073-17692
chr1715184715305E073-17538
chr1715374715438E073-17405
chr1762058762232E07329215
chr1762272762339E07329429
chr1762426762534E07329583
chr1762544762618E07329701
chr1762648763017E07329805
chr1763070763165E07330227
chr1713875714372E074-18471
chr1714448714670E074-18173
chr1714702714752E074-18091
chr1762058762232E07429215
chr1762272762339E07429429
chr1762426762534E07429583
chr1762544762618E07429701
chr1762648763017E07429805
chr1763070763165E07430227
chr1762058762232E08129215
chr1762272762339E08129429
chr1762426762534E08129583
chr1762544762618E08129701
chr1762648763017E08129805
chr1713612713675E082-19168
chr1713875714372E082-18471
chr1714448714670E082-18173
chr1714702714752E082-18091
chr1715081715151E082-17692
chr1715184715305E082-17538
chr1715374715438E082-17405
chr1762058762232E08229215
chr1762272762339E08229429
chr1762426762534E08229583
chr1762544762618E08229701
chr1762648763017E08229805
chr1763070763165E08230227
chr1763672763722E08230829