rs4870976

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0404 (12108/29910,GnomAD)
G==0434 (12662/29118,TOPMED)
G==0400 (2004/5008,1000G)
G==0372 (1432/3854,ALSPAC)
G==0380 (1408/3708,TWINSUK)
chr8:126466080 (GRCh38.p7) (8q24.21)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.126466080G>A
GRCh37.p13 chr 8NC_000008.10:g.127478325G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.539A=0.461
1000GenomesAmericanSub694G=0.310A=0.690
1000GenomesEast AsianSub1008G=0.293A=0.707
1000GenomesEuropeSub1006G=0.404A=0.596
1000GenomesGlobalStudy-wide5008G=0.400A=0.600
1000GenomesSouth AsianSub978G=0.390A=0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.372A=0.628
The Genome Aggregation DatabaseAfricanSub8706G=0.518A=0.482
The Genome Aggregation DatabaseAmericanSub832G=0.280A=0.720
The Genome Aggregation DatabaseEast AsianSub1606G=0.267A=0.733
The Genome Aggregation DatabaseEuropeSub18464G=0.370A=0.629
The Genome Aggregation DatabaseGlobalStudy-wide29910G=0.404A=0.595
The Genome Aggregation DatabaseOtherSub302G=0.320A=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.434A=0.565
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.380A=0.620
PMID Title Author Journal
19581569Genome-wide association study of alcohol dependence.Treutlein JArch Gen Psychiatry

P-Value

SNP ID p-value Traits Study
rs48709766.4E-05alcohol dependence19581569

eQTL of rs4870976 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4870976 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8127509006127509653E06730681
chr8127509673127509768E06731348
chr8127509835127510107E06731510
chr8127509006127509653E06830681
chr8127509673127509768E06831348
chr8127509835127510107E06831510
chr8127504597127504677E07026272
chr8127504792127505095E07026467
chr8127505376127505446E07027051
chr8127439084127439295E071-39030
chr8127439386127439426E071-38899
chr8127509006127509653E07130681
chr8127509673127509768E07131348
chr8127509835127510107E07131510
chr8127510156127510745E07131831
chr8127509006127509653E07230681
chr8127509673127509768E07231348
chr8127509835127510107E07231510
chr8127500378127500960E07322053
chr8127509673127509768E07331348
chr8127509835127510107E07331510
chr8127438724127439077E074-39248
chr8127439084127439295E074-39030
chr8127509006127509653E07430681
chr8127509673127509768E07431348
chr8127509835127510107E07431510
chr8127510156127510745E07431831
chr8127438039127438706E081-39619
chr8127438724127439077E081-39248
chr8127437070127437772E082-40553
chr8127438039127438706E082-39619
chr8127438724127439077E082-39248