rs4871326

Homo sapiens
T>C
ZHX2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0404 (12037/29782,GnomAD)
T==0410 (11940/29118,TOPMED)
T==0398 (1995/5008,1000G)
T==0393 (1513/3854,ALSPAC)
T==0403 (1495/3708,TWINSUK)
chr8:122930907 (GRCh38.p7) (8q24.13)
ND
GWASdb2
1   publication(s)
See rs on genome
274 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.122930907T>C
GRCh37.p13 chr 8NC_000008.10:g.123943147T>C
ZHX2 RefSeqGeneNG_046951.1:g.154559T>C

Gene: ZHX2, zinc fingers and homeoboxes 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZHX2 transcriptNM_014943.3:c.N/AIntron Variant
ZHX2 transcript variant X3XM_005250836.4:c.N/AIntron Variant
ZHX2 transcript variant X1XM_005250837.4:c.N/AIntron Variant
ZHX2 transcript variant X2XM_011516931.2:c.N/AIntron Variant
ZHX2 transcript variant X4XM_011516932.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.402C=0.598
1000GenomesAmericanSub694T=0.290C=0.710
1000GenomesEast AsianSub1008T=0.450C=0.550
1000GenomesEuropeSub1006T=0.396C=0.604
1000GenomesGlobalStudy-wide5008T=0.398C=0.602
1000GenomesSouth AsianSub978T=0.420C=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.393C=0.607
The Genome Aggregation DatabaseAfricanSub8648T=0.418C=0.582
The Genome Aggregation DatabaseAmericanSub836T=0.350C=0.650
The Genome Aggregation DatabaseEast AsianSub1596T=0.449C=0.551
The Genome Aggregation DatabaseEuropeSub18400T=0.395C=0.604
The Genome Aggregation DatabaseGlobalStudy-wide29782T=0.404C=0.595
The Genome Aggregation DatabaseOtherSub302T=0.450C=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.410C=0.589
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.403C=0.597
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs48713260.000489nicotine smoking19268276

eQTL of rs4871326 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4871326 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8123894372123894668E067-48479
chr8123907201123907269E067-35878
chr8123907297123907720E067-35427
chr8123907852123907931E067-35216
chr8123908147123908448E067-34699
chr8123908828123908903E067-34244
chr8123908933123909003E067-34144
chr8123909162123909214E067-33933
chr8123909299123909372E067-33775
chr8123909394123909444E067-33703
chr8123909452123909555E067-33592
chr8123909699123909953E067-33194
chr8123910043123910093E067-33054
chr8123910155123910267E067-32880
chr8123922647123922748E067-20399
chr8123924375123924501E067-18646
chr8123924634123924706E067-18441
chr8123924882123924936E067-18211
chr8123925280123925330E067-17817
chr8123925988123926038E067-17109
chr8123926056123926130E067-17017
chr8123926399123926838E067-16309
chr8123927060123927110E067-16037
chr8123927327123927441E067-15706
chr8123927486123927564E067-15583
chr8123927644123927701E067-15446
chr8123927757123927887E067-15260
chr8123927927123928008E067-15139
chr8123928114123928510E067-14637
chr8123928538123928689E067-14458
chr8123928735123928968E067-14179
chr8123931913123931968E067-11179
chr8123931991123932031E067-11116
chr8123934853123935192E067-7955
chr8123935228123935537E067-7610
chr8123948388123949301E0675241
chr8123981624123981690E06738477
chr8123981691123982833E06738544
chr8123982845123983108E06739698
chr8123983167123983280E06740020
chr8123894053123894097E068-49050
chr8123899239123899315E068-43832
chr8123907201123907269E068-35878
chr8123907297123907720E068-35427
chr8123907852123907931E068-35216
chr8123912895123913014E068-30133
chr8123913118123913172E068-29975
chr8123913546123913666E068-29481
chr8123913699123913953E068-29194
chr8123920265123920422E068-22725
chr8123922439123922609E068-20538
chr8123922647123922748E068-20399
chr8123922862123922941E068-20206
chr8123923042123923146E068-20001
chr8123923192123923363E068-19784
chr8123925988123926038E068-17109
chr8123926056123926130E068-17017
chr8123926399123926838E068-16309
chr8123927060123927110E068-16037
chr8123927327123927441E068-15706
chr8123927486123927564E068-15583
chr8123927644123927701E068-15446
chr8123927757123927887E068-15260
chr8123927927123928008E068-15139
chr8123928114123928510E068-14637
chr8123928538123928689E068-14458
chr8123934041123934834E068-8313
chr8123934853123935192E068-7955
chr8123963006123963241E06819859
chr8123963269123963386E06820122
chr8123963499123963709E06820352
chr8123970817123971007E06827670
chr8123981624123981690E06838477
chr8123981691123982833E06838544
chr8123982845123983108E06839698
chr8123983167123983280E06840020
chr8123894053123894097E069-49050
chr8123894372123894668E069-48479
chr8123907201123907269E069-35878
chr8123907297123907720E069-35427
chr8123907852123907931E069-35216
chr8123908147123908448E069-34699
chr8123909162123909214E069-33933
chr8123909299123909372E069-33775
chr8123909394123909444E069-33703
chr8123909452123909555E069-33592
chr8123909699123909953E069-33194
chr8123910043123910093E069-33054
chr8123910155123910267E069-32880
chr8123925988123926038E069-17109
chr8123926056123926130E069-17017
chr8123926399123926838E069-16309
chr8123927060123927110E069-16037
chr8123927327123927441E069-15706
chr8123927486123927564E069-15583
chr8123927644123927701E069-15446
chr8123927757123927887E069-15260
chr8123927927123928008E069-15139
chr8123928114123928510E069-14637
chr8123928538123928689E069-14458
chr8123928735123928968E069-14179
chr8123953620123953900E06910473
chr8123953955123954085E06910808
chr8123981691123982833E06938544
chr8123894053123894097E070-49050
chr8123894372123894668E070-48479
chr8123898762123898816E070-44331
chr8123898930123899061E070-44086
chr8123899239123899315E070-43832
chr8123899810123899856E070-43291
chr8123907201123907269E070-35878
chr8123907297123907720E070-35427
chr8123907852123907931E070-35216
chr8123908147123908448E070-34699
chr8123921783123921951E070-21196
chr8123921990123922060E070-21087
chr8123922120123922315E070-20832
chr8123922439123922609E070-20538
chr8123922647123922748E070-20399
chr8123925988123926038E070-17109
chr8123926056123926130E070-17017
chr8123926399123926838E070-16309
chr8123927060123927110E070-16037
chr8123927327123927441E070-15706
chr8123927486123927564E070-15583
chr8123927644123927701E070-15446
chr8123927757123927887E070-15260
chr8123927927123928008E070-15139
chr8123928114123928510E070-14637
chr8123928538123928689E070-14458
chr8123928735123928968E070-14179
chr8123954645123955119E07011498
chr8123955137123955254E07011990
chr8123956702123956995E07013555
chr8123981624123981690E07038477
chr8123894053123894097E071-49050
chr8123894372123894668E071-48479
chr8123895363123895537E071-47610
chr8123898762123898816E071-44331
chr8123898930123899061E071-44086
chr8123907201123907269E071-35878
chr8123907297123907720E071-35427
chr8123907852123907931E071-35216
chr8123908147123908448E071-34699
chr8123909699123909953E071-33194
chr8123910043123910093E071-33054
chr8123910155123910267E071-32880
chr8123913546123913666E071-29481
chr8123913699123913953E071-29194
chr8123916609123916649E071-26498
chr8123925988123926038E071-17109
chr8123926056123926130E071-17017
chr8123926399123926838E071-16309
chr8123927060123927110E071-16037
chr8123927327123927441E071-15706
chr8123927486123927564E071-15583
chr8123927644123927701E071-15446
chr8123927757123927887E071-15260
chr8123927927123928008E071-15139
chr8123928114123928510E071-14637
chr8123928538123928689E071-14458
chr8123931913123931968E071-11179
chr8123931991123932031E071-11116
chr8123956702123956995E07113555
chr8123981481123981531E07138334
chr8123981533123981573E07138386
chr8123981624123981690E07138477
chr8123981691123982833E07138544
chr8123982845123983108E07139698
chr8123983167123983280E07140020
chr8123894053123894097E072-49050
chr8123894372123894668E072-48479
chr8123895363123895537E072-47610
chr8123907201123907269E072-35878
chr8123907297123907720E072-35427
chr8123907852123907931E072-35216
chr8123908147123908448E072-34699
chr8123908828123908903E072-34244
chr8123908933123909003E072-34144
chr8123909162123909214E072-33933
chr8123909299123909372E072-33775
chr8123909394123909444E072-33703
chr8123909452123909555E072-33592
chr8123909699123909953E072-33194
chr8123910043123910093E072-33054
chr8123910155123910267E072-32880
chr8123922647123922748E072-20399
chr8123924375123924501E072-18646
chr8123924634123924706E072-18441
chr8123924882123924936E072-18211
chr8123925988123926038E072-17109
chr8123926056123926130E072-17017
chr8123926399123926838E072-16309
chr8123927060123927110E072-16037
chr8123927327123927441E072-15706
chr8123927486123927564E072-15583
chr8123927644123927701E072-15446
chr8123927757123927887E072-15260
chr8123927927123928008E072-15139
chr8123928114123928510E072-14637
chr8123928538123928689E072-14458
chr8123931913123931968E072-11179
chr8123934041123934834E072-8313
chr8123938653123938714E072-4433
chr8123938716123939068E072-4079
chr8123956491123956541E07213344
chr8123956702123956995E07213555
chr8123981624123981690E07238477
chr8123981691123982833E07238544
chr8123982845123983108E07239698
chr8123983167123983280E07240020
chr8123894053123894097E073-49050
chr8123894372123894668E073-48479
chr8123899239123899315E073-43832
chr8123907297123907720E073-35427
chr8123907852123907931E073-35216
chr8123910043123910093E073-33054
chr8123925988123926038E073-17109
chr8123926056123926130E073-17017
chr8123926399123926838E073-16309
chr8123927060123927110E073-16037
chr8123927327123927441E073-15706
chr8123927486123927564E073-15583
chr8123927644123927701E073-15446
chr8123927757123927887E073-15260
chr8123927927123928008E073-15139
chr8123928114123928510E073-14637
chr8123934853123935192E073-7955
chr8123981624123981690E07338477
chr8123981691123982833E07338544
chr8123982845123983108E07339698
chr8123894053123894097E074-49050
chr8123894372123894668E074-48479
chr8123895363123895537E074-47610
chr8123907297123907720E074-35427
chr8123907852123907931E074-35216
chr8123908147123908448E074-34699
chr8123908828123908903E074-34244
chr8123908933123909003E074-34144
chr8123909162123909214E074-33933
chr8123909299123909372E074-33775
chr8123909394123909444E074-33703
chr8123909452123909555E074-33592
chr8123909699123909953E074-33194
chr8123910043123910093E074-33054
chr8123910155123910267E074-32880
chr8123921990123922060E074-21087
chr8123922120123922315E074-20832
chr8123922439123922609E074-20538
chr8123925988123926038E074-17109
chr8123926056123926130E074-17017
chr8123926399123926838E074-16309
chr8123927060123927110E074-16037
chr8123927327123927441E074-15706
chr8123927486123927564E074-15583
chr8123927644123927701E074-15446
chr8123927757123927887E074-15260
chr8123927927123928008E074-15139
chr8123928114123928510E074-14637
chr8123928538123928689E074-14458
chr8123931913123931968E074-11179
chr8123931991123932031E074-11116
chr8123952603123952647E0749456
chr8123952836123952910E0749689
chr8123953070123953120E0749923
chr8123953183123953262E07410036
chr8123981624123981690E07438477
chr8123981691123982833E07438544
chr8123982845123983108E07439698
chr8123983167123983280E07440020
chr8123895998123896097E082-47050
chr8123907201123907269E082-35878
chr8123907297123907720E082-35427
chr8123907852123907931E082-35216