rs4900680

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0485 (14523/29896,GnomAD)
A==0447 (13029/29118,TOPMED)
A==0490 (2453/5008,1000G)
G=0405 (1562/3854,ALSPAC)
G=0412 (1527/3708,TWINSUK)
chr14:45798982 (GRCh38.p7) (14q21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.45798982A>G
GRCh37.p13 chr 14NC_000014.8:g.46268185A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.220G=0.780
1000GenomesAmericanSub694A=0.460G=0.540
1000GenomesEast AsianSub1008A=0.702G=0.298
1000GenomesEuropeSub1006A=0.578G=0.422
1000GenomesGlobalStudy-wide5008A=0.490G=0.510
1000GenomesSouth AsianSub978A=0.570G=0.430
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.595G=0.405
The Genome Aggregation DatabaseAfricanSub8698A=0.304G=0.696
The Genome Aggregation DatabaseAmericanSub838A=0.460G=0.540
The Genome Aggregation DatabaseEast AsianSub1612A=0.696G=0.304
The Genome Aggregation DatabaseEuropeSub18446A=0.600G=0.399
The Genome Aggregation DatabaseGlobalStudy-wide29896A=0.514G=0.485
The Genome Aggregation DatabaseOtherSub302A=0.470G=0.530
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.447G=0.552
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.588G=0.412
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs49006808.9E-05alcoholism (heaviness of drinking)21529783

eQTL of rs4900680 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4900680 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144630796546308051E08139780
chr144630806446308126E08139879
chr144630835946308462E08140174