rs4905720

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0277 (8272/29836,GnomAD)
A==0252 (7343/29118,TOPMED)
A==0361 (1809/5008,1000G)
A==0329 (1269/3854,ALSPAC)
A==0332 (1232/3708,TWINSUK)
chr14:98587627 (GRCh38.p7) (14q32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
33 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.98587627A>G
GRCh37.p13 chr 14NC_000014.8:g.99053964A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.079G=0.921
1000GenomesAmericanSub694A=0.410G=0.590
1000GenomesEast AsianSub1008A=0.764G=0.236
1000GenomesEuropeSub1006A=0.334G=0.666
1000GenomesGlobalStudy-wide5008A=0.361G=0.639
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.329G=0.671
The Genome Aggregation DatabaseAfricanSub8670A=0.115G=0.885
The Genome Aggregation DatabaseAmericanSub838A=0.420G=0.580
The Genome Aggregation DatabaseEast AsianSub1614A=0.738G=0.262
The Genome Aggregation DatabaseEuropeSub18414A=0.306G=0.693
The Genome Aggregation DatabaseGlobalStudy-wide29836A=0.277G=0.722
The Genome Aggregation DatabaseOtherSub300A=0.290G=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.252G=0.747
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.332G=0.668
PMID Title Author Journal
23089632A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.Wang JCMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs49057203.86E-06alcohol dependence23089632

eQTL of rs4905720 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4905720 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr149906079599060873E0676831
chr149910076699100816E06746802
chr149910086099100910E06746896
chr149910094599100995E06746981
chr149905920699059303E0685242
chr149905944099059534E0685476
chr149907924499079361E06825280
chr149909976199100012E06845797
chr149910076699100816E06846802
chr149910086099100910E06846896
chr149910094599100995E06846981
chr149905944099059534E0695476
chr149905973499060130E0695770
chr149905944099059534E0705476
chr149905973499060130E0705770
chr149906079599060873E0706831
chr149909976199100012E07045797
chr149910076699100816E07046802
chr149910086099100910E07046896
chr149910094599100995E07046981
chr149910108099101167E07047116
chr149910180599101867E07047841
chr149905944099059534E0715476
chr149910076699100816E07146802
chr149910086099100910E07146896
chr149910094599100995E07146981
chr149906079599060873E0726831
chr149909976199100012E07345797
chr149910076699100816E07346802
chr149905944099059534E0745476
chr149905973499060130E0745770
chr149909976199100012E07445797
chr149910076699100816E07446802








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr149909097099091030E06837006
chr149910006099100122E06946096
chr149910017799100238E06946213
chr149910006099100122E07146096
chr149910017799100238E07146213
chr149910006099100122E07246096
chr149910017799100238E07246213