rs4909801

Homo sapiens
T>C
LOC101927845 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0268 (8034/29942,GnomAD)
C=0269 (7845/29118,TOPMED)
C=0326 (1632/5008,1000G)
C=0264 (1018/3854,ALSPAC)
C=0286 (1059/3708,TWINSUK)
chr8:134866916 (GRCh38.p7) (8q24.22)
AD
GWASCatalog
1   publication(s)
See rs on genome
44 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.134866916T>C
GRCh37.p13 chr 8NC_000008.10:g.135879159T>C

Gene: LOC101927845, uncharacterized LOC101927845(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101927845 transcriptNR_125427.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.736C=0.264
1000GenomesAmericanSub694T=0.590C=0.410
1000GenomesEast AsianSub1008T=0.593C=0.407
1000GenomesEuropeSub1006T=0.735C=0.265
1000GenomesGlobalStudy-wide5008T=0.674C=0.326
1000GenomesSouth AsianSub978T=0.670C=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.736C=0.264
The Genome Aggregation DatabaseAfricanSub8702T=0.743C=0.257
The Genome Aggregation DatabaseAmericanSub838T=0.600C=0.400
The Genome Aggregation DatabaseEast AsianSub1620T=0.647C=0.353
The Genome Aggregation DatabaseEuropeSub18480T=0.738C=0.261
The Genome Aggregation DatabaseGlobalStudy-wide29942T=0.731C=0.268
The Genome Aggregation DatabaseOtherSub302T=0.820C=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.730C=0.269
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.714C=0.286
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs49098013E-06response to alcohol24277619

eQTL of rs4909801 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4909801 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8135878605135878770E067-389
chr8135879122135879174E0670
chr8135879180135879460E06721
chr8135928131135928485E06748972
chr8135928529135928658E06749370
chr8135836534135836731E068-42428
chr8135836735135836801E068-42358
chr8135837124135837345E068-41814
chr8135878605135878770E068-389
chr8135877960135878524E069-635
chr8135878605135878770E069-389
chr8135927516135927605E06948357
chr8135927748135927818E06948589
chr8135927924135927974E06948765
chr8135928131135928485E06948972
chr8135928529135928658E06949370
chr8135877960135878524E071-635
chr8135878605135878770E071-389
chr8135879122135879174E0710
chr8135927748135927818E07148589
chr8135927924135927974E07148765
chr8135928131135928485E07148972
chr8135928529135928658E07149370
chr8135877960135878524E072-635
chr8135878605135878770E072-389
chr8135879122135879174E0720
chr8135879180135879460E07221
chr8135928131135928485E07248972
chr8135928529135928658E07249370
chr8135928529135928658E07349370
chr8135929013135929087E07349854
chr8135877960135878524E074-635
chr8135878605135878770E074-389
chr8135879122135879174E0740
chr8135879180135879460E07421
chr8135879475135879750E074316
chr8135879754135879874E074595
chr8135909610135910175E07430451
chr8135910278135910441E07431119
chr8135910524135910568E07431365
chr8135928131135928485E07448972
chr8135928529135928658E07449370
chr8135928131135928485E08148972
chr8135850041135850774E082-28385









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8135842218135846135E067-33024
chr8135842218135846135E068-33024
chr8135842218135846135E069-33024
chr8135842218135846135E070-33024
chr8135842218135846135E071-33024
chr8135842218135846135E072-33024
chr8135842218135846135E073-33024
chr8135842218135846135E074-33024
chr8135842218135846135E082-33024