rs4910291

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0318 (9509/29880,GnomAD)
G==0301 (8784/29118,TOPMED)
G==0301 (1507/5008,1000G)
G==0289 (1113/3854,ALSPAC)
G==0294 (1092/3708,TWINSUK)
chr11:11268524 (GRCh38.p7) (11p15.4)
AD
GWASdb2
1   publication(s)
See rs on genome
107 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.11268524G>A
GRCh37.p13 chr 11NC_000011.9:g.11290071G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.318A=0.682
1000GenomesAmericanSub694G=0.330A=0.670
1000GenomesEast AsianSub1008G=0.303A=0.697
1000GenomesEuropeSub1006G=0.286A=0.714
1000GenomesGlobalStudy-wide5008G=0.301A=0.699
1000GenomesSouth AsianSub978G=0.270A=0.730
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.289A=0.711
The Genome Aggregation DatabaseAfricanSub8692G=0.322A=0.678
The Genome Aggregation DatabaseAmericanSub834G=0.320A=0.680
The Genome Aggregation DatabaseEast AsianSub1612G=0.298A=0.702
The Genome Aggregation DatabaseEuropeSub18440G=0.319A=0.680
The Genome Aggregation DatabaseGlobalStudy-wide29880G=0.318A=0.681
The Genome Aggregation DatabaseOtherSub302G=0.250A=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.301A=0.698
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.294A=0.706
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs49102910.000801alcohol dependence20201924

eQTL of rs4910291 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4910291 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr111125789211257974E067-32097
chr111125801311258948E067-31123
chr111128527411285490E067-4581
chr111128565011285700E067-4371
chr111130661811306700E06716547
chr111130709211307206E06717021
chr111133499711335346E06744926
chr111125789211257974E068-32097
chr111126451911266607E068-23464
chr111128474711284836E068-5235
chr111128494311285015E068-5056
chr111128501711285170E068-4901
chr111128527411285490E068-4581
chr111128565011285700E068-4371
chr111130661811306700E06816547
chr111130709211307206E06817021
chr111130731911307617E06817248
chr111131115511311205E06821084
chr111131138811311442E06821317
chr111133499711335346E06844926
chr111133547011335888E06845399
chr111124051311240600E069-49471
chr111126451911266607E069-23464
chr111128527411285490E069-4581
chr111130661811306700E06916547
chr111130709211307206E06917021
chr111130731911307617E06917248
chr111133499711335346E06944926
chr111133547011335888E06945399
chr111133593611336132E06945865
chr111133627511336360E06946204
chr111133639611336460E06946325
chr111131783311317883E07027762
chr111131802611318450E07027955
chr111131845811318576E07028387
chr111131885611318915E07028785
chr111125766411257772E071-32299
chr111125789211257974E071-32097
chr111125801311258948E071-31123
chr111126437311264433E071-25638
chr111126451911266607E071-23464
chr111128527411285490E071-4581
chr111128690511287890E071-2181
chr111128790811287990E071-2081
chr111130709211307206E07117021
chr111130731911307617E07117248
chr111130761911307699E07117548
chr111131090211311002E07120831
chr111131115511311205E07121084
chr111131138811311442E07121317
chr111133439011334516E07144319
chr111133499711335346E07144926
chr111133547011335888E07145399
chr111133593611336132E07145865
chr111124051311240600E072-49471
chr111125766411257772E072-32299
chr111125789211257974E072-32097
chr111126451911266607E072-23464
chr111128474711284836E072-5235
chr111128494311285015E072-5056
chr111130661811306700E07216547
chr111130709211307206E07217021
chr111130731911307617E07217248
chr111133547011335888E07245399
chr111128474711284836E073-5235
chr111128494311285015E073-5056
chr111128501711285170E073-4901
chr111130234111302391E07312270
chr111130240811302458E07312337
chr111130252111302607E07312450
chr111130260911302772E07312538
chr111130709211307206E07317021
chr111130731911307617E07317248
chr111130828611308336E07318215
chr111131115511311205E07321084
chr111131138811311442E07321317
chr111133499711335346E07344926
chr111133547011335888E07345399
chr111133593611336132E07345865
chr111133627511336360E07346204
chr111133639611336460E07346325
chr111124051311240600E074-49471
chr111124064611240730E074-49341
chr111124082311240873E074-49198
chr111125766411257772E074-32299
chr111125789211257974E074-32097
chr111126451911266607E074-23464
chr111130595111306016E07415880
chr111130605411306129E07415983
chr111130615811306362E07416087
chr111130648611306588E07416415
chr111130661811306700E07416547
chr111130709211307206E07417021
chr111130731911307617E07417248
chr111130761911307699E07417548
chr111133547011335888E07445399
chr111133593611336132E07445865
chr111133627511336360E07446204
chr111125603511256252E081-33819
chr111125628211256341E081-33730
chr111125639511256471E081-33600
chr111125652711256587E081-33484
chr111126451911266607E081-23464
chr111125603511256252E082-33819
chr111125628211256341E082-33730
chr111125639511256471E082-33600
chr111125652711256587E082-33484