rs4932598

Homo sapiens
T>C
SLCO3A1 : Intron Variant
LOC107984747 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0174 (5235/29970,GnomAD)
C=0152 (4442/29118,TOPMED)
C=0216 (1081/5008,1000G)
C=0167 (645/3854,ALSPAC)
C=0171 (634/3708,TWINSUK)
chr15:91994615 (GRCh38.p7) (15q26.1)
ND
GWASdb2
2   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.91994615T>C
GRCh37.p13 chr 15NC_000015.9:g.92537845T>C

Gene: SLCO3A1, solute carrier organic anion transporter family member 3A1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLCO3A1 transcript variant 2NM_001145044.1:c.N/AIntron Variant
SLCO3A1 transcript variant 1NM_013272.3:c.N/AIntron Variant
SLCO3A1 transcript variant 3NR_135775.1:n.N/AIntron Variant
SLCO3A1 transcript variant X1XM_005254889.1:c.N/AIntron Variant
SLCO3A1 transcript variant X3XM_005254891.2:c.N/AIntron Variant
SLCO3A1 transcript variant X2XM_011521456.2:c.N/AIntron Variant
SLCO3A1 transcript variant X4XR_931795.1:n.N/AIntron Variant
SLCO3A1 transcript variant X5XR_931796.2:n.N/AIntron Variant

Gene: LOC107984747, uncharacterized LOC107984747(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107984747 transcriptXR_001751660.1:n....XR_001751660.1:n.13860T>CT>CNon Coding Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.928C=0.072
1000GenomesAmericanSub694T=0.670C=0.330
1000GenomesEast AsianSub1008T=0.663C=0.337
1000GenomesEuropeSub1006T=0.809C=0.191
1000GenomesGlobalStudy-wide5008T=0.784C=0.216
1000GenomesSouth AsianSub978T=0.770C=0.230
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.833C=0.167
The Genome Aggregation DatabaseAfricanSub8730T=0.909C=0.091
The Genome Aggregation DatabaseAmericanSub836T=0.600C=0.400
The Genome Aggregation DatabaseEast AsianSub1616T=0.684C=0.316
The Genome Aggregation DatabaseEuropeSub18486T=0.809C=0.190
The Genome Aggregation DatabaseGlobalStudy-wide29970T=0.825C=0.174
The Genome Aggregation DatabaseOtherSub302T=0.770C=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.847C=0.152
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.829C=0.171
PMID Title Author Journal
18227835Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.Berrettini WMol Psychiatry
20460270Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.Garcia-Barcelo MMHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs49325980.000192nicotine dependence18227835

eQTL of rs4932598 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4932598 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159248787792487917E067-49928
chr159248791892488077E067-49768
chr159248917492489224E067-48621
chr159248928992489426E067-48419
chr159248946492489565E067-48280
chr159248957592489665E067-48180
chr159248967692489732E067-48113
chr159248974892489854E067-47991
chr159249014692492222E067-45623
chr159249229392492455E067-45390
chr159249559192495831E067-42014
chr159249588892496110E067-41735
chr159249614392496383E067-41462
chr159249647192497199E067-40646
chr159249733092497520E067-40325
chr159249753992497883E067-39962
chr159250594792505997E067-31848
chr159250819092508290E067-29555
chr159250858392509865E067-27980
chr159250993392510212E067-27633
chr159251029192510335E067-27510
chr159251058092510630E067-27215
chr159251097792511406E067-26439
chr159251149792511724E067-26121
chr159251185392512133E067-25712
chr159251215892512232E067-25613
chr159251230992512359E067-25486
chr159251291792512962E067-24883
chr159251303492513086E067-24759
chr159251317992514068E067-23777
chr159251652292516604E067-21241
chr159251684592516976E067-20869
chr159251703692517118E067-20727
chr159251731992517392E067-20453
chr159251743092517474E067-20371
chr159251762792517872E067-19973
chr159251799792518050E067-19795
chr159251856692518776E067-19069
chr159251879192519179E067-18666
chr159252901192529068E067-8777
chr159252912192529223E067-8622
chr159253222892532278E067-5567
chr159253229892532439E067-5406
chr159253406192534276E067-3569
chr159253468592534762E067-3083
chr159253568292535749E067-2096
chr159253580792535875E067-1970
chr159253595292536078E067-1767
chr159254390092543957E0676055
chr159254400792544394E0676162
chr159254448192544556E0676636
chr159254466892544883E0676823
chr159254493092545052E0677085
chr159254510492545336E0677259
chr159254681692546970E0678971
chr159254710192547229E0679256
chr159254728492547359E0679439
chr159254746392547572E0679618
chr159254767092547720E0679825
chr159254939592549456E06711550
chr159254951992549859E06711674
chr159255004392550103E06712198
chr159255026792550307E06712422
chr159255184292552026E06713997
chr159255205392552142E06714208
chr159255235692552456E06714511
chr159255248792552640E06714642
chr159255266592552753E06714820
chr159255281892552868E06714973
chr159255294292552992E06715097
chr159255318492553298E06715339
chr159255419692554264E06716351
chr159255430792554357E06716462
chr159255454692554639E06716701
chr159255476092555808E06716915
chr159255585692555936E06718011
chr159255613092556193E06718285
chr159255624692556290E06718401
chr159255636192556449E06718516
chr159255647392556523E06718628
chr159255653892556609E06718693
chr159255661492556720E06718769
chr159255698392557033E06719138
chr159255735092557400E06719505
chr159255744392557568E06719598
chr159255762392557828E06719778
chr159255787192557921E06720026
chr159255799192558157E06720146
chr159255888292558941E06721037
chr159255897592559025E06721130
chr159256066092561866E06722815
chr159256502692565076E06727181
chr159256512292565223E06727277
chr159256523692565297E06727391
chr159256543292565485E06727587
chr159256553492565584E06727689
chr159256578692565846E06727941
chr159256591592565971E06728070
chr159257070492570847E06732859
chr159257087392570961E06733028
chr159257112692571253E06733281
chr159257129292571342E06733447
chr159257137492572807E06733529
chr159257297992573495E06735134
chr159257357592573700E06735730
chr159257402292574503E06736177
chr159257456892574700E06736723
chr159257478292574851E06736937
chr159257594792576010E06738102
chr159257649092577126E06738645
chr159257715992577234E06739314
chr159257728392577333E06739438
chr159257894992579035E06741104
chr159257914392579337E06741298
chr159257935792579569E06741512
chr159258442592584475E06746580
chr159258530192585518E06747456
chr159258571192585761E06747866
chr159258577692585833E06747931
chr159248787792487917E068-49928
chr159248791892488077E068-49768
chr159248883692488950E068-48895
chr159248917492489224E068-48621
chr159248928992489426E068-48419
chr159248946492489565E068-48280
chr159248957592489665E068-48180
chr159248967692489732E068-48113
chr159248974892489854E068-47991
chr159248987392490079E068-47766
chr159249014692492222E068-45623
chr159249922492500003E068-37842
chr159250819092508290E068-29555
chr159250858392509865E068-27980
chr159250993392510212E068-27633
chr159251029192510335E068-27510
chr159251058092510630E068-27215
chr159251097792511406E068-26439
chr159251149792511724E068-26121
chr159251185392512133E068-25712
chr159251215892512232E068-25613
chr159251230992512359E068-25486
chr159251291792512962E068-24883
chr159251303492513086E068-24759
chr159251317992514068E068-23777
chr159251410192514163E068-23682
chr159251417392514307E068-23538
chr159251452992514579E068-23266
chr159251473292514800E068-23045
chr159251480392514853E068-22992
chr159251500392515096E068-22749
chr159251684592516976E068-20869
chr159251703692517118E068-20727
chr159251731992517392E068-20453
chr159251743092517474E068-20371
chr159251762792517872E068-19973
chr159251799792518050E068-19795
chr159251856692518776E068-19069
chr159251879192519179E068-18666
chr159252251492522653E068-15192
chr159252269492522744E068-15101
chr159252278892522902E068-14943
chr159252295292523125E068-14720
chr159252317692523590E068-14255
chr159252834392528454E068-9391
chr159252880292528852E068-8993
chr159252887592528982E068-8863
chr159253352992533688E068-4157
chr159253373492533860E068-3985
chr159253406192534276E068-3569
chr159254666592546778E0688820
chr159254681692546970E0688971
chr159254710192547229E0689256
chr159254728492547359E0689439
chr159254746392547572E0689618
chr159254767092547720E0689825
chr159254782392547871E0689978
chr159254847292548851E06810627
chr159254897492549028E06811129
chr159254908392549253E06811238
chr159254939592549456E06811550
chr159254951992549859E06811674
chr159255004392550103E06812198
chr159255026792550307E06812422
chr159255062992550716E06812784
chr159255235692552456E06814511
chr159255248792552640E06814642
chr159255266592552753E06814820
chr159255281892552868E06814973
chr159255294292552992E06815097
chr159255318492553298E06815339
chr159255357092553645E06815725
chr159255419692554264E06816351
chr159255430792554357E06816462
chr159255454692554639E06816701
chr159255476092555808E06816915
chr159255585692555936E06818011
chr159255613092556193E06818285
chr159255624692556290E06818401
chr159255636192556449E06818516
chr159255647392556523E06818628
chr159255653892556609E06818693
chr159255661492556720E06818769
chr159255698392557033E06819138
chr159255735092557400E06819505
chr159255744392557568E06819598
chr159255762392557828E06819778
chr159255787192557921E06820026
chr159255799192558157E06820146
chr159256212292562524E06824277
chr159256502692565076E06827181
chr159256512292565223E06827277
chr159256523692565297E06827391
chr159256722792567435E06829382
chr159256743892567521E06829593
chr159256766492567708E06829819
chr159256860592568880E06830760
chr159256899292569271E06831147
chr159256946492569514E06831619
chr159256954692569586E06831701
chr159257649092577126E06838645
chr159257715992577234E06839314
chr159257728392577333E06839438
chr159258442592584475E06846580
chr159258514892585198E06847303
chr159258530192585518E06847456
chr159258571192585761E06847866
chr159258577692585833E06847931
chr159248787792487917E069-49928
chr159248791892488077E069-49768
chr159248917492489224E069-48621
chr159248928992489426E069-48419
chr159248946492489565E069-48280
chr159248957592489665E069-48180
chr159248967692489732E069-48113
chr159248974892489854E069-47991
chr159248987392490079E069-47766
chr159249014692492222E069-45623
chr159249229392492455E069-45390
chr159249330292493713E069-44132
chr159249647192497199E069-40646
chr159249794192498026E069-39819
chr159249814592498252E069-39593
chr159249834492498394E069-39451
chr159249841792498508E069-39337
chr159249909192499223E069-38622
chr159250574692505822E069-32023
chr159250594792505997E069-31848
chr159250603692506123E069-31722
chr159250819092508290E069-29555
chr159250858392509865E069-27980
chr159250993392510212E069-27633
chr159251029192510335E069-27510
chr159251058092510630E069-27215
chr159251097792511406E069-26439
chr159251149792511724E069-26121
chr159251185392512133E069-25712
chr159251215892512232E069-25613
chr159251230992512359E069-25486
chr159251291792512962E069-24883
chr159251303492513086E069-24759
chr159251317992514068E069-23777
chr159251410192514163E069-23682
chr159251417392514307E069-23538
chr159251452992514579E069-23266
chr159251473292514800E069-23045
chr159251480392514853E069-22992
chr159251641392516486E069-21359
chr159251652292516604E069-21241
chr159251684592516976E069-20869
chr159251703692517118E069-20727
chr159251731992517392E069-20453
chr159251743092517474E069-20371
chr159251762792517872E069-19973
chr159251799792518050E069-19795
chr159251856692518776E069-19069
chr159251879192519179E069-18666
chr159252317692523590E069-14255
chr159252422292524371E069-13474
chr159252834392528454E069-9391
chr159252851092528560E069-9285
chr159252880292528852E069-8993
chr159252887592528982E069-8863
chr159253332192533401E069-4444
chr159253352992533688E069-4157
chr159253373492533860E069-3985
chr159253406192534276E069-3569
chr159253540092535450E069-2395
chr159253568292535749E069-2096
chr159253580792535875E069-1970
chr159253595292536078E069-1767
chr159253609092536208E069-1637
chr159253625592536543E069-1302
chr159253662592536706E069-1139
chr159253802792538106E069182
chr159253866492538704E069819
chr159254390092543957E0696055
chr159254400792544394E0696162
chr159254466892544883E0696823
chr159254641892546483E0698573
chr159254652692546596E0698681
chr159254666592546778E0698820
chr159254681692546970E0698971
chr159254710192547229E0699256
chr159254728492547359E0699439
chr159254746392547572E0699618
chr159254767092547720E0699825
chr159254782392547871E0699978
chr159254908392549253E06911238
chr159254939592549456E06911550
chr159254951992549859E06911674
chr159255004392550103E06912198
chr159255026792550307E06912422
chr159255062992550716E06912784
chr159255281892552868E06914973
chr159255294292552992E06915097
chr159255318492553298E06915339
chr159255357092553645E06915725
chr159255419692554264E06916351
chr159255430792554357E06916462
chr159255454692554639E06916701
chr159255476092555808E06916915
chr159255585692555936E06918011
chr159255613092556193E06918285
chr159255624692556290E06918401
chr159255636192556449E06918516
chr159255647392556523E06918628
chr159255653892556609E06918693
chr159255661492556720E06918769
chr159255698392557033E06919138
chr159255735092557400E06919505
chr159255744392557568E06919598
chr159255762392557828E06919778
chr159255787192557921E06920026
chr159255799192558157E06920146
chr159255888292558941E06921037
chr159255897592559025E06921130
chr159255968892559766E06921843
chr159255990392559953E06922058
chr159256033292560400E06922487
chr159256066092561866E06922815
chr159256212292562524E06924277
chr159256282392562888E06924978
chr159256293292562996E06925087
chr159256311392563165E06925268
chr159256317292563257E06925327
chr159256722792567435E06929382
chr159256743892567521E06929593
chr159256766492567708E06929819
chr159256812792568224E06930282
chr159256840492568452E06930559
chr159256860592568880E06930760
chr159256899292569271E06931147
chr159256946492569514E06931619
chr159256954692569586E06931701
chr159257297992573495E06935134
chr159257357592573700E06935730
chr159257402292574503E06936177
chr159257456892574700E06936723
chr159257478292574851E06936937
chr159257511392575157E06937268
chr159257524292575284E06937397
chr159257552592575575E06937680
chr159257594792576010E06938102
chr159257649092577126E06938645
chr159257715992577234E06939314
chr159257728392577333E06939438
chr159257761392577718E06939768
chr159257894992579035E06941104
chr159257914392579337E06941298
chr159257935792579569E06941512
chr159258471392584962E06946868
chr159258514892585198E06947303
chr159258530192585518E06947456
chr159258571192585761E06947866
chr159258577692585833E06947931
chr159258603992586096E06948194
chr159254400792544394E0706162
chr159254448192544556E0706636
chr159254466892544883E0706823
chr159254493092545052E0707085
chr159248787792487917E071-49928
chr159248791892488077E071-49768
chr159248917492489224E071-48621
chr159248928992489426E071-48419
chr159248946492489565E071-48280
chr159248957592489665E071-48180
chr159248967692489732E071-48113
chr159248974892489854E071-47991
chr159248987392490079E071-47766
chr159249014692492222E071-45623
chr159249229392492455E071-45390
chr159249272892492809E071-45036
chr159249287292492922E071-44923
chr159249295092492990E071-44855
chr159249330292493713E071-44132
chr159249380892494561E071-43284
chr159249457492494728E071-43117
chr159249513492495203E071-42642
chr159249559192495831E071-42014
chr159249588892496110E071-41735
chr159249614392496383E071-41462
chr159249647192497199E071-40646
chr159249733092497520E071-40325
chr159249753992497883E071-39962
chr159249794192498026E071-39819
chr159249814592498252E071-39593
chr159249834492498394E071-39451
chr159249841792498508E071-39337
chr159249896992499036E071-38809
chr159249909192499223E071-38622
chr159250453092504879E071-32966
chr159250492892504982E071-32863
chr159250501292505088E071-32757
chr159250574692505822E071-32023
chr159250594792505997E071-31848
chr159250603692506123E071-31722
chr159250742492507474E071-30371
chr159250751192507585E071-30260
chr159250763492507689E071-30156
chr159250819092508290E071-29555
chr159250858392509865E071-27980
chr159250993392510212E071-27633
chr159251029192510335E071-27510
chr159251058092510630E071-27215
chr159251097792511406E071-26439
chr159251149792511724E071-26121
chr159251185392512133E071-25712
chr159251215892512232E071-25613
chr159251230992512359E071-25486
chr159251291792512962E071-24883
chr159251303492513086E071-24759
chr159251317992514068E071-23777
chr159251410192514163E071-23682
chr159251417392514307E071-23538
chr159251452992514579E071-23266
chr159251473292514800E071-23045
chr159251480392514853E071-22992
chr159251500392515096E071-22749
chr159251553092515610E071-22235
chr159251568692515730E071-22115
chr159251641392516486E071-21359
chr159251652292516604E071-21241
chr159251684592516976E071-20869
chr159251703692517118E071-20727
chr159251731992517392E071-20453
chr159251743092517474E071-20371
chr159251762792517872E071-19973
chr159251799792518050E071-19795
chr159251856692518776E071-19069
chr159251879192519179E071-18666
chr159252278892522902E071-14943
chr159252295292523125E071-14720
chr159252317692523590E071-14255
chr159252422292524371E071-13474
chr159252499992525111E071-12734
chr159252652592526772E071-11073
chr159252686892526940E071-10905
chr159252697292527505E071-10340
chr159252834392528454E071-9391
chr159252851092528560E071-9285
chr159252880292528852E071-8993
chr159252887592528982E071-8863
chr159252901192529068E071-8777
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chr159254448192544556E0826636
chr159254466892544883E0826823
chr159255430792554357E08216462
chr159255476092555808E08216915