rs4937598

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0383 (11477/29920,GnomAD)
A=0359 (10458/29118,TOPMED)
A=0394 (1974/5008,1000G)
A=0382 (1473/3854,ALSPAC)
A=0382 (1417/3708,TWINSUK)
chr11:131064722 (GRCh38.p7) (11q25)
AD
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.131064722G>A
GRCh37.p13 chr 11NC_000011.9:g.130934617G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.741A=0.259
1000GenomesAmericanSub694G=0.530A=0.470
1000GenomesEast AsianSub1008G=0.527A=0.473
1000GenomesEuropeSub1006G=0.595A=0.405
1000GenomesGlobalStudy-wide5008G=0.606A=0.394
1000GenomesSouth AsianSub978G=0.570A=0.430
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.618A=0.382
The Genome Aggregation DatabaseAfricanSub8710G=0.705A=0.295
The Genome Aggregation DatabaseAmericanSub834G=0.470A=0.530
The Genome Aggregation DatabaseEast AsianSub1614G=0.563A=0.437
The Genome Aggregation DatabaseEuropeSub18460G=0.587A=0.412
The Genome Aggregation DatabaseGlobalStudy-wide29920G=0.616A=0.383
The Genome Aggregation DatabaseOtherSub302G=0.520A=0.480
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.640A=0.359
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.618A=0.382
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs49375980.000212alcohol dependence20201924

eQTL of rs4937598 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4937598 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11130901392130901434E070-33183
chr11130901593130901643E070-32974
chr11130906403130906699E070-27918
chr11130906742130906792E070-27825
chr11130916753130916840E070-17777
chr11130916943130917023E070-17594
chr11130920865130920915E070-13702
chr11130921202130921306E070-13311
chr11130921437130921512E070-13105
chr11130921573130921794E070-12823
chr11130921991130922178E070-12439
chr11130922196130922416E070-12201
chr11130934132130934935E0700
chr11130934941130935001E070324
chr11130935418130935802E070801
chr11130935873130936165E0701256
chr11130935418130935802E071801
chr11130935873130936165E0711256
chr11130922196130922416E081-12201
chr11130933233130933378E081-1239
chr11130933430130934119E081-498
chr11130934132130934935E0810
chr11130934941130935001E081324
chr11130935418130935802E081801
chr11130935873130936165E0811256
chr11130932869130932995E082-1622
chr11130933233130933378E082-1239
chr11130933430130934119E082-498
chr11130934132130934935E0820
chr11130934941130935001E082324
chr11130935418130935802E082801
chr11130935873130936165E0821256