rs4941342

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0187 (5606/29908,GnomAD)
C=0160 (4662/29118,TOPMED)
C=0203 (1015/5008,1000G)
C=0208 (802/3854,ALSPAC)
C=0183 (679/3708,TWINSUK)
chr18:65527982 (GRCh38.p7) (18q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.65527982T>C
GRCh37.p13 chr 18NC_000018.9:g.63195218T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.872C=0.128
1000GenomesAmericanSub694T=0.820C=0.180
1000GenomesEast AsianSub1008T=0.619C=0.381
1000GenomesEuropeSub1006T=0.810C=0.190
1000GenomesGlobalStudy-wide5008T=0.797C=0.203
1000GenomesSouth AsianSub978T=0.850C=0.150
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.792C=0.208
The Genome Aggregation DatabaseAfricanSub8712T=0.861C=0.139
The Genome Aggregation DatabaseAmericanSub838T=0.840C=0.160
The Genome Aggregation DatabaseEast AsianSub1608T=0.659C=0.341
The Genome Aggregation DatabaseEuropeSub18448T=0.801C=0.198
The Genome Aggregation DatabaseGlobalStudy-wide29908T=0.812C=0.187
The Genome Aggregation DatabaseOtherSub302T=0.860C=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.839C=0.160
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.817C=0.183
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs49413420.00045alcohol dependence20201924

eQTL of rs4941342 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4941342 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.