rs4944137

Homo sapiens
G>C
LOC105369399 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0234 (6835/29118,TOPMED)
G==0318 (9231/29032,GnomAD)
G==0327 (1637/5008,1000G)
G==0360 (1386/3854,ALSPAC)
G==0366 (1356/3708,TWINSUK)
chr11:77047545 (GRCh38.p7) (11q13.5)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.77047545G>C
GRCh37.p13 chr 11 fix patch HG414_PATCHNW_003871081.1:g.49182G>C
GRCh37.p13 chr 11NC_000011.9:g.76758592G>C

Gene: LOC105369399, uncharacterized LOC105369399(plus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
LOC105369399 transcriptXR_950340.1:n.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.059C=0.941
1000GenomesAmericanSub694G=0.340C=0.660
1000GenomesEast AsianSub1008G=0.463C=0.537
1000GenomesEuropeSub1006G=0.365C=0.635
1000GenomesGlobalStudy-wide5008G=0.327C=0.673
1000GenomesSouth AsianSub978G=0.500C=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.360C=0.640
The Genome Aggregation DatabaseAfricanSub8594G=0.094C=0.906
The Genome Aggregation DatabaseAmericanSub794G=0.390C=0.610
The Genome Aggregation DatabaseEast AsianSub1608G=0.479C=0.521
The Genome Aggregation DatabaseEuropeSub17738G=0.408C=0.591
The Genome Aggregation DatabaseGlobalStudy-wide29032G=0.318C=0.682
The Genome Aggregation DatabaseOtherSub298G=0.310C=0.690
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.234C=0.765
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.366C=0.634
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs49441370.000799alcohol dependence21314694

eQTL of rs4944137 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4944137 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.