| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 15 | NC_000015.10:g.100575243C>A |
| GRCh37.p13 chr 15 | NC_000015.9:g.101115448C>A |
| LINS1 RefSeqGene | NG_034076.1:g.31998G>T |
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| LINS1 transcript variant 1 | NM_001040616.2:c. | N/A | Intron Variant |
| LINS1 transcript variant X1 | XM_005254941.1:c. | N/A | Intron Variant |
| LINS1 transcript variant X2 | XM_005254943.1:c. | N/A | Intron Variant |
| LINS1 transcript variant X3 | XM_017022398.1:c. | N/A | Intron Variant |
| LINS1 transcript variant X4 | XM_017022399.1:c. | N/A | Intron Variant |
| LINS1 transcript variant X7 | XM_017022400.1:c. | N/A | Intron Variant |
| LINS1 transcript variant X5 | XR_001751346.1:n. | N/A | Intron Variant |
| LINS1 transcript variant X9 | XR_001751347.1:n. | N/A | Intron Variant |
| LINS1 transcript variant X11 | XR_001751348.1:n. | N/A | Intron Variant |
| LINS1 transcript variant X10 | XR_243210.3:n. | N/A | Intron Variant |
| LINS1 transcript variant X12 | XR_429464.3:n. | N/A | Intron Variant |
| LINS1 transcript variant X6 | XR_931862.2:n. | N/A | Intron Variant |
| LINS1 transcript variant X8 | XR_931863.2:n. | N/A | Intron Variant |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | C=0.187 | A=0.813 |
| 1000Genomes | American | Sub | 694 | C=0.220 | A=0.780 |
| 1000Genomes | East Asian | Sub | 1008 | C=0.612 | A=0.388 |
| 1000Genomes | Europe | Sub | 1006 | C=0.087 | A=0.913 |
| 1000Genomes | Global | Study-wide | 5008 | C=0.250 | A=0.750 |
| 1000Genomes | South Asian | Sub | 978 | C=0.150 | A=0.850 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | C=0.090 | A=0.910 |
| The Genome Aggregation Database | African | Sub | 8718 | C=0.162 | A=0.838 |
| The Genome Aggregation Database | American | Sub | 838 | C=0.190 | A=0.810 |
| The Genome Aggregation Database | East Asian | Sub | 1604 | C=0.669 | A=0.331 |
| The Genome Aggregation Database | Europe | Sub | 18494 | C=0.085 | A=0.915 |
| The Genome Aggregation Database | Global | Study-wide | 29956 | C=0.143 | A=0.856 |
| The Genome Aggregation Database | Other | Sub | 302 | C=0.250 | A=0.750 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | C=0.147 | A=0.852 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | C=0.091 | A=0.909 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 20201924 | Genome-wide association study of alcohol dependence implicates a region on chromosome 11. | Edenberg HJ | Alcohol Clin Exp Res |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs4965678 | 0.000715 | alcohol dependence | 20201924 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue |
|---|---|---|---|---|---|---|
| Chr15:101115448 | CERS3 | ENSG00000154227.9 | C>A | 6.3302e-11 | 30248 | Cerebellum |
| Chr15:101115448 | CERS3 | ENSG00000154227.9 | C>A | 1.4305e-9 | 30248 | Cerebellar_Hemisphere |
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr15 | 101144841 | 101144895 | E067 | 29393 |
| chr15 | 101144965 | 101145043 | E067 | 29517 |
| chr15 | 101065746 | 101066988 | E068 | -48460 |
| chr15 | 101140459 | 101140499 | E068 | 25011 |
| chr15 | 101140537 | 101140587 | E068 | 25089 |
| chr15 | 101140873 | 101140917 | E068 | 25425 |
| chr15 | 101065746 | 101066988 | E069 | -48460 |
| chr15 | 101140459 | 101140499 | E069 | 25011 |
| chr15 | 101140537 | 101140587 | E069 | 25089 |
| chr15 | 101140873 | 101140917 | E069 | 25425 |
| chr15 | 101065600 | 101065685 | E070 | -49763 |
| chr15 | 101065746 | 101066988 | E070 | -48460 |
| chr15 | 101071519 | 101071674 | E070 | -43774 |
| chr15 | 101072034 | 101072084 | E070 | -43364 |
| chr15 | 101072273 | 101072561 | E070 | -42887 |
| chr15 | 101138928 | 101139055 | E070 | 23480 |
| chr15 | 101139098 | 101139323 | E070 | 23650 |
| chr15 | 101065746 | 101066988 | E071 | -48460 |
| chr15 | 101139098 | 101139323 | E071 | 23650 |
| chr15 | 101065746 | 101066988 | E072 | -48460 |
| chr15 | 101102583 | 101102693 | E072 | -12755 |
| chr15 | 101140873 | 101140917 | E072 | 25425 |
| chr15 | 101065746 | 101066988 | E074 | -48460 |
| chr15 | 101065600 | 101065685 | E081 | -49763 |
| chr15 | 101065746 | 101066988 | E081 | -48460 |
| chr15 | 101070215 | 101070505 | E081 | -44943 |
| chr15 | 101140873 | 101140917 | E081 | 25425 |
| chr15 | 101065746 | 101066988 | E082 | -48460 |
| chr15 | 101070215 | 101070505 | E082 | -44943 |
| chr15 | 101072034 | 101072084 | E082 | -43364 |
| chr15 | 101072273 | 101072561 | E082 | -42887 |
| chr15 | 101140873 | 101140917 | E082 | 25425 |
| Chromosome | Start | End | Region | Distance(-/+:Up/Downstream) |
|---|---|---|---|---|
| chr15 | 101141028 | 101143692 | E067 | 25580 |
| chr15 | 101141028 | 101143692 | E068 | 25580 |
| chr15 | 101141028 | 101143692 | E069 | 25580 |
| chr15 | 101141028 | 101143692 | E070 | 25580 |
| chr15 | 101141028 | 101143692 | E071 | 25580 |
| chr15 | 101141028 | 101143692 | E072 | 25580 |
| chr15 | 101141028 | 101143692 | E073 | 25580 |
| chr15 | 101141028 | 101143692 | E074 | 25580 |
| chr15 | 101141028 | 101143692 | E081 | 25580 |
| chr15 | 101141028 | 101143692 | E082 | 25580 |