rs4969069

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0072 (2166/29966,GnomAD)
C==0086 (2514/29118,TOPMED)
C==0088 (441/5008,1000G)
C==0038 (145/3854,ALSPAC)
C==0039 (146/3708,TWINSUK)
chr17:73134434 (GRCh38.p7) (17q25.1)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.73134434C>T
GRCh37.p13 chr 17NC_000017.10:g.71130573C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.150T=0.850
1000GenomesAmericanSub694C=0.110T=0.890
1000GenomesEast AsianSub1008C=0.089T=0.911
1000GenomesEuropeSub1006C=0.036T=0.964
1000GenomesGlobalStudy-wide5008C=0.088T=0.912
1000GenomesSouth AsianSub978C=0.040T=0.960
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.038T=0.962
The Genome Aggregation DatabaseAfricanSub8714C=0.132T=0.868
The Genome Aggregation DatabaseAmericanSub838C=0.120T=0.880
The Genome Aggregation DatabaseEast AsianSub1618C=0.091T=0.909
The Genome Aggregation DatabaseEuropeSub18494C=0.040T=0.959
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.072T=0.927
The Genome Aggregation DatabaseOtherSub302C=0.090T=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.086T=0.913
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.039T=0.961
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs49690690.000893alcohol dependence21314694

eQTL of rs4969069 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs4969069 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr177108482771084877E067-45696
chr177108497971085127E067-45446
chr177108516471085214E067-45359
chr177108554671085596E067-44977
chr177108593071086256E067-44317
chr177108650671086954E067-43619
chr177108740371087443E067-43130
chr177108183571081879E068-48694
chr177108211771082167E068-48406
chr177108482771084877E068-45696
chr177108497971085127E068-45446
chr177108516471085214E068-45359
chr177108554671085596E068-44977
chr177108715371087266E068-43307
chr177108740371087443E068-43130
chr177115134371152977E06820770
chr177108448171084660E069-45913
chr177108497971085127E069-45446
chr177108516471085214E069-45359
chr177108650671086954E069-43619
chr177108740371087443E069-43130
chr177109305271093658E069-36915
chr177115134371152977E06920770
chr177115986371159948E06929290
chr177108650671086954E070-43619
chr177114298371143149E07012410
chr177114319771143247E07012624
chr177115116771151221E07020594
chr177115134371152977E07020770
chr177115302671154027E07022453
chr177115418071154292E07023607
chr177108448171084660E071-45913
chr177108482771084877E071-45696
chr177108497971085127E071-45446
chr177108715371087266E071-43307
chr177108740371087443E071-43130
chr177115116771151221E07120594
chr177115134371152977E07120770
chr177115746371157866E07126890
chr177108448171084660E072-45913
chr177108593071086256E072-44317
chr177108650671086954E072-43619
chr177108697071087070E072-43503
chr177108715371087266E072-43307
chr177108740371087443E072-43130
chr177115134371152977E07220770
chr177108448171084660E073-45913
chr177108482771084877E073-45696
chr177108497971085127E073-45446
chr177108516471085214E073-45359
chr177108554671085596E073-44977
chr177108650671086954E073-43619
chr177108697071087070E073-43503
chr177108715371087266E073-43307
chr177115134371152977E07320770
chr177116543771165497E07334864
chr177116566071165724E07335087
chr177117880771179402E07348234
chr177108211771082167E074-48406
chr177108448171084660E074-45913
chr177108697071087070E074-43503
chr177108715371087266E074-43307
chr177108740371087443E074-43130
chr177109523271095410E074-35163
chr177109570971095940E074-34633
chr177115134371152977E07420770
chr177116601171166071E07435438
chr177115025071150304E08119677
chr177115053171150617E08119958
chr177115069971150753E08120126
chr177115077471150934E08120201
chr177115116771151221E08120594
chr177115134371152977E08120770
chr177115302671154027E08122453
chr177115418071154292E08123607
chr177115431371154435E08123740
chr177115447871154528E08123905
chr177115457871154641E08124005
chr177116601171166071E08135438
chr177116615371166230E08135580
chr177117315571173207E08142582
chr177117364071173775E08143067
chr177108593071086256E082-44317
chr177108650671086954E082-43619
chr177108956571089651E082-40922
chr177108970671089787E082-40786
chr177111439471114459E082-16114
chr177111447371114547E082-16026
chr177111457871114721E082-15852
chr177111487771114971E082-15602
chr177111506471115313E082-15260
chr177111538271115525E082-15048
chr177115025071150304E08219677
chr177115053171150617E08219958
chr177115069971150753E08220126
chr177115077471150934E08220201
chr177115116771151221E08220594
chr177115134371152977E08220770
chr177115302671154027E08222453
chr177115457871154641E08224005
chr177115468971154747E08224116
chr177117404071174092E08243467
chr177117429371174374E08243720
chr177117880771179402E08248234
chr177117943371179499E08248860










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr177108766171089396E067-41177
chr177116037571162561E06729802
chr177108766171089396E068-41177
chr177116037571162561E06829802
chr177108766171089396E069-41177
chr177108766171089396E070-41177
chr177108766171089396E071-41177
chr177116037571162561E07129802
chr177108766171089396E072-41177
chr177116037571162561E07229802
chr177108766171089396E073-41177
chr177116037571162561E07329802
chr177108766171089396E074-41177
chr177116037571162561E07429802
chr177108766171089396E081-41177
chr177108766171089396E082-41177
chr177116037571162561E08229802