rs5002773

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
C==0458 (13624/29708,GnomAD)
C==0460 (13414/29118,TOPMED)
C==0448 (2246/5008,1000G)
chr4:35518928 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35518928C>G
GRCh37.p13 chr 4NC_000004.11:g.35520550C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.400G=0.600
1000GenomesAmericanSub694C=0.520G=0.480
1000GenomesEast AsianSub1008C=0.298G=0.702
1000GenomesEuropeSub1006C=0.464G=0.536
1000GenomesGlobalStudy-wide5008C=0.448G=0.552
1000GenomesSouth AsianSub978C=0.600G=0.400
The Genome Aggregation DatabaseAfricanSub8666C=0.414G=0.586
The Genome Aggregation DatabaseAmericanSub828C=0.570G=0.430
The Genome Aggregation DatabaseEast AsianSub1602C=0.260G=0.740
The Genome Aggregation DatabaseEuropeSub18310C=0.492G=0.507
The Genome Aggregation DatabaseGlobalStudy-wide29708C=0.458G=0.541
The Genome Aggregation DatabaseOtherSub302C=0.420G=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.460G=0.539
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs50027730.000257nicotine dependence17158188

eQTL of rs5002773 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5002773 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E0746187
chr43553670135536912E08216151
chr43553699835537160E08216448


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E0686322
chr43552703435527236E0686484
chr43552753335527608E0686983
chr43552687235526986E0696322
chr43552703435527236E0696484
chr43552687235526986E0716322
chr43552703435527236E0716484
chr43552753335527608E0716983
chr43552687235526986E0726322
chr43552703435527236E0726484
chr43552687235526986E0736322
chr43552703435527236E0736484
chr43552687235526986E0746322
chr43552703435527236E0746484