rs5002776

Homo sapiens
A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0458 (13673/29842,GnomAD)
A==0460 (13419/29118,TOPMED)
A==0448 (2244/5008,1000G)
chr4:35518855 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35518855A>T
GRCh37.p13 chr 4NC_000004.11:g.35520477A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.400T=0.600
1000GenomesAmericanSub694A=0.520T=0.480
1000GenomesEast AsianSub1008A=0.299T=0.701
1000GenomesEuropeSub1006A=0.462T=0.538
1000GenomesGlobalStudy-wide5008A=0.448T=0.552
1000GenomesSouth AsianSub978A=0.600T=0.400
The Genome Aggregation DatabaseAfricanSub8692A=0.413T=0.587
The Genome Aggregation DatabaseAmericanSub838A=0.570T=0.430
The Genome Aggregation DatabaseEast AsianSub1612A=0.262T=0.738
The Genome Aggregation DatabaseEuropeSub18398A=0.492T=0.507
The Genome Aggregation DatabaseGlobalStudy-wide29842A=0.458T=0.541
The Genome Aggregation DatabaseOtherSub302A=0.420T=0.580
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.460T=0.539
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs50027760.00026nicotine dependence17158188

eQTL of rs5002776 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5002776 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E0746260
chr43553670135536912E08216224
chr43553699835537160E08216521


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E0686395
chr43552703435527236E0686557
chr43552753335527608E0687056
chr43552687235526986E0696395
chr43552703435527236E0696557
chr43552687235526986E0716395
chr43552703435527236E0716557
chr43552753335527608E0717056
chr43552687235526986E0726395
chr43552703435527236E0726557
chr43552687235526986E0736395
chr43552703435527236E0736557
chr43552687235526986E0746395
chr43552703435527236E0746557