rs526992

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0084 (2529/29894,GnomAD)
T==0085 (2500/29118,TOPMED)
T==0069 (347/5008,1000G)
T==0122 (470/3854,ALSPAC)
T==0123 (455/3708,TWINSUK)
chr3:166310918 (GRCh38.p7) (3q26.1)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.166310918T>C
GRCh37.p13 chr 3NC_000003.11:g.166028706T>C
GRCh38.p7 chr 3 alt locus HSCHR3_3_CTG2_1NT_187536.1:g.10135T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.022C=0.978
1000GenomesAmericanSub694T=0.110C=0.890
1000GenomesEast AsianSub1008T=0.036C=0.964
1000GenomesEuropeSub1006T=0.114C=0.886
1000GenomesGlobalStudy-wide5008T=0.069C=0.931
1000GenomesSouth AsianSub978T=0.090C=0.910
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.122C=0.878
The Genome Aggregation DatabaseAfricanSub8714T=0.032C=0.968
The Genome Aggregation DatabaseAmericanSub834T=0.130C=0.870
The Genome Aggregation DatabaseEast AsianSub1622T=0.044C=0.956
The Genome Aggregation DatabaseEuropeSub18422T=0.110C=0.889
The Genome Aggregation DatabaseGlobalStudy-wide29894T=0.084C=0.915
The Genome Aggregation DatabaseOtherSub302T=0.120C=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.085C=0.914
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.123C=0.877
PMID Title Author Journal
21956439Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.Zuo LNeuropsychopharmacology

P-Value

SNP ID p-value Traits Study
rs5269924E-06alcohol dependence21956439

eQTL of rs526992 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs526992 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3166078286166078442E08149580
chr3166078446166078496E08149740

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3166001563166001971E068-26735
chr3166001563166001971E069-26735
chr3166001563166001971E071-26735
chr3166001563166001971E072-26735
chr3166001563166001971E074-26735