SNP Detail Info-rs528301

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0283 (8496/29942,GnomAD)
G==0245 (7132/29116,TOPMED)
G==0153 (765/5008,1000G)
G==0441 (1699/3854,ALSPAC)
G==0439 (1628/3708,TWINSUK)

Position: chr2:44927769 (GRCh38.p7) (2p21)

Phenotype: ND

Dataset:

GWASdb2 | GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 21 Enhancers around

Promoter: 27 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.44927769G>A
GRCh37.p13 chr 2	NC_000002.11:g.45154908G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.030	A=0.970
1000Genomes	American	Sub	694	G=0.210	A=0.790
1000Genomes	East Asian	Sub	1008	G=0.025	A=0.975
1000Genomes	Europe	Sub	1006	G=0.429	A=0.571
1000Genomes	Global	Study-wide	5008	G=0.153	A=0.847
1000Genomes	South Asian	Sub	978	G=0.130	A=0.870
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.441	A=0.559
The Genome Aggregation Database	African	Sub	8722	G=0.086	A=0.914
The Genome Aggregation Database	American	Sub	838	G=0.220	A=0.780
The Genome Aggregation Database	East Asian	Sub	1622	G=0.012	A=0.988
The Genome Aggregation Database	Europe	Sub	18458	G=0.402	A=0.597
The Genome Aggregation Database	Global	Study-wide	29942	G=0.283	A=0.716
The Genome Aggregation Database	Other	Sub	302	G=0.360	A=0.640
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.245	A=0.755
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.439	A=0.561

PMID	Title	Author	Journal
22488850	Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.	Zuo L	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs528301	5E-06	alcohol and nictotine co-dependence	22488850

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	45199910	45200582	E067	45002
chr2	45200695	45200798	E067	45787
chr2	45192267	45192391	E068	37359
chr2	45192749	45192836	E068	37841
chr2	45141668	45141783	E070	-13125
chr2	45142596	45142663	E070	-12245
chr2	45173567	45173683	E070	18659
chr2	45183505	45183708	E070	28597
chr2	45183714	45183893	E070	28806
chr2	45183909	45183982	E070	29001
chr2	45184910	45185001	E070	30002
chr2	45185057	45185122	E070	30149
chr2	45185214	45185311	E070	30306
chr2	45185494	45185590	E070	30586
chr2	45191153	45191354	E070	36245
chr2	45192267	45192391	E070	37359
chr2	45183505	45183708	E081	28597
chr2	45184910	45185001	E081	30002
chr2	45185057	45185122	E081	30149
chr2	45185214	45185311	E081	30306
chr2	45185494	45185590	E081	30586

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	45167857	45169348	E067	12949
chr2	45155643	45156087	E068	735
chr2	45163917	45166211	E068	9009
chr2	45166266	45166500	E068	11358
chr2	45167857	45169348	E068	12949
chr2	45169488	45170176	E068	14580
chr2	45171020	45172393	E068	16112
chr2	45179173	45180578	E068	24265
chr2	45167857	45169348	E069	12949
chr2	45169488	45170176	E069	14580
chr2	45179173	45180578	E069	24265
chr2	45166266	45166500	E070	11358
chr2	45167857	45169348	E070	12949
chr2	45169488	45170176	E070	14580
chr2	45171020	45172393	E070	16112
chr2	45167857	45169348	E071	12949
chr2	45171020	45172393	E071	16112
chr2	45155643	45156087	E072	735
chr2	45167857	45169348	E072	12949
chr2	45169488	45170176	E072	14580
chr2	45155643	45156087	E073	735
chr2	45167857	45169348	E073	12949
chr2	45169488	45170176	E073	14580
chr2	45155643	45156087	E074	735
chr2	45167857	45169348	E074	12949
chr2	45169488	45170176	E074	14580
chr2	45167857	45169348	E082	12949

rs528301