rs563816

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0359 (10754/29932,GnomAD)
T=0471 (13718/29118,TOPMED)
T=0354 (1772/5008,1000G)
T=0212 (816/3854,ALSPAC)
T=0225 (834/3708,TWINSUK)
chr11:106360417 (GRCh38.p7) (11q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.106360417C>T
GRCh37.p13 chr 11NC_000011.9:g.106231144C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.195T=0.805
1000GenomesAmericanSub694C=0.790T=0.210
1000GenomesEast AsianSub1008C=0.887T=0.113
1000GenomesEuropeSub1006C=0.747T=0.253
1000GenomesGlobalStudy-wide5008C=0.646T=0.354
1000GenomesSouth AsianSub978C=0.800T=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.788T=0.212
The Genome Aggregation DatabaseAfricanSub8702C=0.275T=0.725
The Genome Aggregation DatabaseAmericanSub838C=0.780T=0.220
The Genome Aggregation DatabaseEast AsianSub1612C=0.898T=0.102
The Genome Aggregation DatabaseEuropeSub18478C=0.782T=0.217
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.640T=0.359
The Genome Aggregation DatabaseOtherSub302C=0.700T=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.528T=0.471
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.775T=0.225
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs5638167.17E-06alcohol and nictotine co-dependence20158304

eQTL of rs563816 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs563816 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11106181967106182074E068-49070
chr11106182304106182385E068-48759
chr11106182506106182567E068-48577
chr11106182304106182385E070-48759
chr11106182506106182567E070-48577
chr11106182641106182908E070-48236
chr11106214636106215168E073-15976
chr11106197607106197827E081-33317
chr11106197885106198218E081-32926
chr11106198259106198329E081-32815
chr11106198484106198689E081-32455
chr11106214636106215168E081-15976
chr11106215204106215483E081-15661
chr11106216471106216546E081-14598
chr11106216606106216679E081-14465
chr11106214636106215168E082-15976
chr11106215204106215483E082-15661