rs567338

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0323 (9669/29928,GnomAD)
A=0385 (11212/29118,TOPMED)
A=0467 (2337/5008,1000G)
A=0212 (818/3854,ALSPAC)
A=0212 (785/3708,TWINSUK)
chr18:7488972 (GRCh38.p7) (18p11.23)
ND
GWASdb2
1   publication(s)
See rs on genome
42 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.7488972G>A
GRCh37.p13 chr 18NC_000018.9:g.7488970G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.360A=0.640
1000GenomesAmericanSub694G=0.710A=0.290
1000GenomesEast AsianSub1008G=0.405A=0.595
1000GenomesEuropeSub1006G=0.794A=0.206
1000GenomesGlobalStudy-wide5008G=0.533A=0.467
1000GenomesSouth AsianSub978G=0.510A=0.490
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.788A=0.212
The Genome Aggregation DatabaseAfricanSub8698G=0.430A=0.570
The Genome Aggregation DatabaseAmericanSub836G=0.720A=0.280
The Genome Aggregation DatabaseEast AsianSub1602G=0.371A=0.629
The Genome Aggregation DatabaseEuropeSub18490G=0.817A=0.182
The Genome Aggregation DatabaseGlobalStudy-wide29928G=0.676A=0.323
The Genome Aggregation DatabaseOtherSub302G=0.710A=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.614A=0.385
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.788A=0.212
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs5673383.7E-05alcohol and nictotine co-dependence20158304

eQTL of rs567338 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs567338 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1874589787459133E067-29837
chr1874594617459511E067-29459
chr1874614197461485E067-27485
chr1874589787459133E068-29837
chr1874594617459511E068-29459
chr1874614197461485E068-27485
chr1875123367512398E06823366
chr1875124417512651E06823471
chr1874589787459133E069-29837
chr1874594617459511E069-29459
chr1874559847456032E070-32938
chr1874565157456686E070-32284
chr1874568437456964E070-32006
chr1874570807457160E070-31810
chr1874572547457595E070-31375
chr1874589787459133E070-29837
chr1874594617459511E070-29459
chr1874673757467468E070-21502
chr1875123367512398E07023366
chr1875124417512651E07023471
chr1875128147512891E07023844
chr1874589787459133E071-29837
chr1874594617459511E071-29459
chr1874614197461485E071-27485
chr1874589787459133E072-29837
chr1874594617459511E072-29459
chr1874614197461485E072-27485
chr1874594617459511E073-29459
chr1874589787459133E074-29837
chr1874594617459511E074-29459
chr1874614197461485E074-27485
chr1874818527483498E074-5472
chr1874836977483785E074-5185
chr1874598187460170E081-28800
chr1874614197461485E081-27485
chr1875123367512398E08123366
chr1875124417512651E08123471
chr1875128147512891E08123844
chr1875131757513265E08124205
chr1874565157456686E082-32284
chr1874594617459511E082-29459
chr1874598187460170E082-28800










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1874602197460786E067-28184
chr1874608327460999E067-27971
chr1874602197460786E068-28184
chr1874608327460999E068-27971
chr1874602197460786E069-28184
chr1874608327460999E069-27971
chr1874602197460786E070-28184
chr1874602197460786E071-28184
chr1874608327460999E071-27971
chr1874602197460786E072-28184
chr1874608327460999E072-27971
chr1874602197460786E073-28184
chr1874608327460999E073-27971
chr1874602197460786E074-28184
chr1874608327460999E074-27971