rs569612

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
C==0131 (3952/29962,GnomAD)
C==0136 (3974/29118,TOPMED)
C==0160 (802/5008,1000G)
C==0134 (516/3854,ALSPAC)
C==0120 (445/3708,TWINSUK)
chr11:95380889 (GRCh38.p7) (11q21)
AD
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.95380889C>A
GRCh37.p13 chr 11NC_000011.9:g.95114053C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.153A=0.847
1000GenomesAmericanSub694C=0.190A=0.810
1000GenomesEast AsianSub1008C=0.240A=0.760
1000GenomesEuropeSub1006C=0.117A=0.883
1000GenomesGlobalStudy-wide5008C=0.160A=0.840
1000GenomesSouth AsianSub978C=0.110A=0.890
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.134A=0.866
The Genome Aggregation DatabaseAfricanSub8724C=0.146A=0.854
The Genome Aggregation DatabaseAmericanSub838C=0.160A=0.840
The Genome Aggregation DatabaseEast AsianSub1616C=0.231A=0.769
The Genome Aggregation DatabaseEuropeSub18482C=0.115A=0.884
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.131A=0.868
The Genome Aggregation DatabaseOtherSub302C=0.170A=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.136A=0.863
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.120A=0.880
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs5696120.000613alcohol consumption (maxi-drinks)24277619

eQTL of rs569612 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs569612 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr119507008995073225E067-40828
chr119507008995073225E068-40828
chr119515258395152777E06838530
chr119507008995073225E069-40828
chr119506895595069554E070-44499
chr119506969195069745E070-44308
chr119506995995070009E070-44044
chr119507008995073225E070-40828
chr119509680095097162E070-16891
chr119509722895097410E070-16643
chr119509744095097490E070-16563
chr119507008995073225E071-40828
chr119507008995073225E072-40828
chr119507008995073225E073-40828
chr119507008995073225E074-40828
chr119507008995073225E081-40828
chr119507008995073225E082-40828