rs57126985

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0089 (2149/23892,GnomAD)
C=0079 (395/5008,1000G)
chr21:15217712 (GRCh38.p7) (21q21.1)
AD
GWASCatalog
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 21NC_000021.9:g.15217712G>C
GRCh37.p13 chr 21NC_000021.8:g.16590032G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.738C=0.262
1000GenomesAmericanSub694G=0.980C=0.020
1000GenomesEast AsianSub1008G=1.000C=0.000
1000GenomesEuropeSub1006G=0.984C=0.016
1000GenomesGlobalStudy-wide5008G=0.921C=0.079
1000GenomesSouth AsianSub978G=0.980C=0.020
The Genome Aggregation DatabaseAfricanSub7892G=0.776C=0.224
The Genome Aggregation DatabaseAmericanSub714G=0.980C=0.020
The Genome Aggregation DatabaseEast AsianSub1262G=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub13804G=0.973C=0.026
The Genome Aggregation DatabaseGlobalStudy-wide23892G=0.910C=0.089
The Genome Aggregation DatabaseOtherSub220G=0.980C=0.020
PMID Title Author Journal
26365420The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.Mbarek HAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs571269856E-06alcohol dependence26365420

eQTL of rs57126985 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs57126985 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr211659410116594837E0684069
chr211661299316613043E07022961
chr211661433116615245E07024299
chr211663740116637441E07047369
chr211663777016637830E07047738
chr211659287116593096E0812839
chr211659311516593194E0813083
chr211659319616593296E0813164