rs57369046

Homo sapiens
T>C
LINC01324 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0136 (4075/29954,GnomAD)
C=0173 (5044/29118,TOPMED)
C=0147 (738/5008,1000G)
C=0104 (400/3854,ALSPAC)
C=0107 (395/3708,TWINSUK)
chr3:164831898 (GRCh38.p7) (3q26.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.164831898T>C
GRCh37.p13 chr 3NC_000003.11:g.164549686T>C

Gene: LINC01324, long intergenic non-protein coding RNA 1324(minus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
LINC01324 transcriptNR_126405.1:n.N/AUpstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.725C=0.275
1000GenomesAmericanSub694T=0.920C=0.080
1000GenomesEast AsianSub1008T=0.905C=0.095
1000GenomesEuropeSub1006T=0.907C=0.093
1000GenomesGlobalStudy-wide5008T=0.853C=0.147
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.896C=0.104
The Genome Aggregation DatabaseAfricanSub8714T=0.747C=0.253
The Genome Aggregation DatabaseAmericanSub836T=0.940C=0.060
The Genome Aggregation DatabaseEast AsianSub1618T=0.898C=0.102
The Genome Aggregation DatabaseEuropeSub18484T=0.912C=0.087
The Genome Aggregation DatabaseGlobalStudy-wide29954T=0.864C=0.136
The Genome Aggregation DatabaseOtherSub302T=0.910C=0.090
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.826C=0.173
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.893C=0.107
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs573690466.06E-08alcohol dependence (age at onset)24962325

eQTL of rs57369046 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs57369046 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.