rs5746647

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0101 (3047/29926,GnomAD)
G==0140 (4083/29116,TOPMED)
G==0100 (502/5008,1000G)
chr22:16576248 (GRCh38.p7) (22q11.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
76 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.16576248G>T
GRCh37.p13 chr 22NC_000022.10:g.17057138G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.256T=0.744
1000GenomesAmericanSub694G=0.060T=0.940
1000GenomesEast AsianSub1008G=0.012T=0.988
1000GenomesEuropeSub1006G=0.059T=0.941
1000GenomesGlobalStudy-wide5008G=0.100T=0.900
1000GenomesSouth AsianSub978G=0.050T=0.950
The Genome Aggregation DatabaseAfricanSub8710G=0.233T=0.767
The Genome Aggregation DatabaseAmericanSub834G=0.050T=0.950
The Genome Aggregation DatabaseEast AsianSub1612G=0.009T=0.991
The Genome Aggregation DatabaseEuropeSub18470G=0.051T=0.948
The Genome Aggregation DatabaseGlobalStudy-wide29926G=0.101T=0.898
The Genome Aggregation DatabaseOtherSub300G=0.070T=0.930
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.140T=0.859
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs57466470.000864alcohol dependence20201924

eQTL of rs5746647 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5746647 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr221708165017081739E06724512
chr221708183217083108E06724694
chr221708367517083772E06726537
chr221708382217083983E06726684
chr221708403817084146E06726900
chr221708428817084338E06727150
chr221708165017081739E06824512
chr221708183217083108E06824694
chr221708318017083244E06826042
chr221708329517083353E06826157
chr221708343017083527E06826292
chr221708367517083772E06826537
chr221708382217083983E06826684
chr221708403817084146E06826900
chr221708428817084338E06827150
chr221709046017090544E06833322
chr221709086217090975E06833724
chr221708183217083108E06924694
chr221708318017083244E06926042
chr221708329517083353E06926157
chr221708343017083527E06926292
chr221708367517083772E06926537
chr221708382217083983E06926684
chr221708403817084146E06926900
chr221708183217083108E07024694
chr221708318017083244E07026042
chr221708329517083353E07026157
chr221708343017083527E07026292
chr221708367517083772E07026537
chr221708382217083983E07026684
chr221708165017081739E07124512
chr221708183217083108E07124694
chr221708318017083244E07126042
chr221708329517083353E07126157
chr221708343017083527E07126292
chr221708367517083772E07126537
chr221708382217083983E07126684
chr221708403817084146E07126900
chr221708428817084338E07127150
chr221708441317084744E07127275
chr221709012817090229E07132990
chr221709046017090544E07133322
chr221709086217090975E07133724
chr221708165017081739E07224512
chr221708183217083108E07224694
chr221708318017083244E07226042
chr221708329517083353E07226157
chr221708343017083527E07226292
chr221708367517083772E07226537
chr221708382217083983E07226684
chr221708403817084146E07226900
chr221708428817084338E07227150
chr221708441317084744E07227275
chr221708994917090022E07232811
chr221709012817090229E07232990
chr221709046017090544E07233322
chr221709086217090975E07233724
chr221708183217083108E07324694
chr221708367517083772E07326537
chr221708382217083983E07326684
chr221708403817084146E07326900
chr221708165017081739E07424512
chr221708183217083108E07424694
chr221708318017083244E07426042
chr221708329517083353E07426157
chr221708343017083527E07426292
chr221708367517083772E07426537
chr221708382217083983E07426684
chr221708403817084146E07426900
chr221708428817084338E07427150
chr221708441317084744E07427275
chr221708183217083108E08224694
chr221708318017083244E08226042
chr221708329517083353E08226157
chr221708343017083527E08226292
chr221709086217090975E08233724