rs576192

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0455 (13625/29914,GnomAD)
T==0441 (12841/29118,TOPMED)
T==0353 (1769/5008,1000G)
G=0280 (1078/3854,ALSPAC)
G=0277 (1027/3708,TWINSUK)
chr18:7519003 (GRCh38.p7) (18p11.23)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.7519003T>A
GRCh38.p7 chr 18NC_000018.10:g.7519003T>G
GRCh37.p13 chr 18NC_000018.9:g.7519001T>A
GRCh37.p13 chr 18NC_000018.9:g.7519001T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.080G=0.920
1000GenomesAmericanSub694T=0.560G=0.440
1000GenomesEast AsianSub1008T=0.245G=0.755
1000GenomesEuropeSub1006T=0.724G=0.276
1000GenomesGlobalStudy-wide5008T=0.353G=0.647
1000GenomesSouth AsianSub978T=0.310G=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.720G=0.280
The Genome Aggregation DatabaseAfricanSub8704T=0.164A=0.000
The Genome Aggregation DatabaseAmericanSub836T=0.560A=0.00,
The Genome Aggregation DatabaseEast AsianSub1618T=0.219A=0.000
The Genome Aggregation DatabaseEuropeSub18454T=0.750A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.544A=0.000
The Genome Aggregation DatabaseOtherSub302T=0.650A=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.441G=0.559
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.723G=0.277
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs5761923.06E-05alcohol and nictotine co-dependence20158304

eQTL of rs576192 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs576192 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.