rs577196

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0454 (13562/29866,GnomAD)
C==0419 (12220/29118,TOPMED)
C==0473 (2369/5008,1000G)
C==0499 (1924/3854,ALSPAC)
T=0495 (1834/3708,TWINSUK)
chr3:118439050 (GRCh38.p7) (3q13.32)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.118439050C>T
GRCh37.p13 chr 3NC_000003.11:g.118157897C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.315T=0.685
1000GenomesAmericanSub694C=0.520T=0.480
1000GenomesEast AsianSub1008C=0.567T=0.433
1000GenomesEuropeSub1006C=0.517T=0.483
1000GenomesGlobalStudy-wide5008C=0.473T=0.527
1000GenomesSouth AsianSub978C=0.510T=0.490
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.499T=0.501
The Genome Aggregation DatabaseAfricanSub8698C=0.351T=0.649
The Genome Aggregation DatabaseAmericanSub834C=0.540T=0.460
The Genome Aggregation DatabaseEast AsianSub1600C=0.557T=0.443
The Genome Aggregation DatabaseEuropeSub18432C=0.490T=0.509
The Genome Aggregation DatabaseGlobalStudy-wide29866C=0.454T=0.545
The Genome Aggregation DatabaseOtherSub302C=0.410T=0.590
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.419T=0.580
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.505T=0.495
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs5771960.00027alcohol dependence20201924

eQTL of rs577196 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs577196 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3118144864118145163E081-12734
chr3118152707118152993E081-4904
chr3118153567118153668E081-4229