| 19132693 | Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. | Chen X | Am J Med Genet B Neuropsychiatr Genet |
| 20624154 | Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes. | Grucza RA | Addict Biol |
| 23689675 | Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents. | Nees F | Neuropsychopharmacology |
| 21748402 | A twin association study of nicotine dependence with markers in the CHRNA3 and CHRNA5 genes. | Maes HH | Behav Genet |
| 22046326 | 'Smoking genes': a genetic association study. | Verde Z | PLoS One |
| 18414406 | Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. | Wang JC | Mol Psychiatry |
| 19443489 | Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. | Wang JC | Hum Mol Genet |
| 20808433 | Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population. | Li MD | PLoS One |
| 24375168 | ADHD diagnosis may influence the association between polymorphisms in nicotinic acetylcholine receptor genes and tobacco smoking. | Polina ER | Neuromolecular Med |
| 23143843 | Molecular mechanisms underlying behaviors related to nicotine addiction. | Picciotto MR | Cold Spring Harb Perspect Med |
| 20643934 | A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction. | Hong LE | Proc Natl Acad Sci U S A |
| 20886544 | Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance. | Winterer G | Am J Med Genet B Neuropsychiatr Genet |
| 19596527 | Nicotine dependence and genetic variation in the nicotinic receptors. | Bierut LJ | Drug Alcohol Depend |
| 17135278 | Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. | Saccone SF | Hum Mol Genet |
| 24065931 | The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers. | Robinson JD | Front Psychiatry |
| 20393456 | Sensorimotor gating is associated with CHRNA3 polymorphisms in schizophrenia and healthy volunteers. | Petrovsky N | Neuropsychopharmacology |
| 23397474 | Polymorphisms of CHRNA5-CHRNA3-CHRNB4 Gene Cluster and NSCLC Risk in Chinese Population. | Li Z | Transl Oncol |
| 27166759 | Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions. | Yang J | Mol Psychiatry |
| 19259974 | Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. | Saccone NL | Am J Med Genet B Neuropsychiatr Genet |
| 20485328 | Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. | Sherva R | Neuropsychopharmacology |
| 25051068 | Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analyses. | Cui K | PLoS One |
| 25632390 | Association between genetic variants on chromosome 15q25 locus and several nicotine dependence traits in Polish population: a case-control study. | Buczkowski K | Biomed Res Int |
| 19859904 | Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. | Li MD | Am J Med Genet B Neuropsychiatr Genet |
| 21606948 | Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes. | Swan GE | Pharmacogenomics J |
| 25139936 | Association of cancer susceptibility variants with risk of multiple primary cancers: The population architecture using genomics and epidemiology study. | Park SL | Cancer Epidemiol Biomarkers Prev |
| 24588897 | CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women. | Criado JR | Twin Res Hum Genet |
| 18783506 | Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. | Sherva R | Addiction |
| 19184766 | A testable prognostic model of nicotine dependence. | Ramoni RB | J Neurogenet |
| 20736995 | Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstrom test for nicotine dependence. | Wessel J | Neuropsychopharmacology |
| 22992668 | Pharmacogenomics knowledge for personalized medicine. | Whirl-Carrillo M | Clin Pharmacol Ther |
| 19436041 | Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. | Baker TB | Nicotine Tob Res |
| 22832964 | Genome-wide meta-analyses of smoking behaviors in African Americans. | David SP | Transl Psychiatry |
| 21191315 | Genetic association of bipolar disorder with the beta(3) nicotinic receptor subunit gene. | Hartz SM | Psychiatr Genet |
| 26044620 | Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction. | Reyes-Gibby CC | BMC Syst Biol |
| 24186853 | Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. | Stephens SH | Genet Epidemiol |
| 20587604 | Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans. | Hansen HM | Hum Mol Genet |
| 19247474 | Genome-wide and candidate gene association study of cigarette smoking behaviors. | Caporaso N | PLoS One |
| 22438940 | Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. | Kapoor M | PLoS One |
| 22539395 | Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. | Chen LS | Genet Epidemiol |
| 25874685 | CHRNA3 rs6495308 genotype as an effect modifier of the association between daily cigarette consumption and hypertension in Chinese male smokers. | Wu XY | Int J Environ Res Public Health |
| 25036316 | Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study. | Zhu Y | PLoS One |
| 21559498 | Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk. | Wang Y | PLoS One |
| 18618000 | A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. | Weiss RB | PLoS Genet |
| 20418888 | Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. | Thorgeirsson TE | Nat Genet |
| 26981579 | Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. | David SP | EBioMedicine |
| 20840187 | Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence. | Johnson EO | Addiction |
| 27197960 | Association between variants in nicotinic acetylcholine receptor genes and smoking cessation in a Chinese rural population. | Wang Q | Am J Addict |
| 21810735 | Single nucleotide polymorphisms in CHRNA5 rs16969968, CHRNA3 rs578776, and LOC123688 rs8034191 are associated with heaviness of smoking in women in Northeastern Ontario, Canada. | Conlon MS | Nicotine Tob Res |
| 22806211 | The genetics of addiction-a translational perspective. | Agrawal A | Transl Psychiatry |
| 21385908 | Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. | Falcone M | Nicotine Tob Res |
| 20631687 | Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility. | Zhang H | Neuropsychopharmacology |
| 21808284 | Gender-stratified gene and gene-treatment interactions in smoking cessation. | Lee W | Pharmacogenomics J |
| 25642160 | Nicotinic receptor modulation to treat alcohol and drug dependence. | Rahman S | Front Neurosci |
| 18519524 | Variants in nicotinic receptors and risk for nicotine dependence. | Bierut LJ | Am J Psychiatry |
| 22176972 | Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis. | Zhang J | Respir Res |
| 18565990 | Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. | Saccone SF | Bioinformatics |
| 26695521 | Mendelian Randomization - the Key to Understanding Aspects of Parkinson's Disease Causation? | Noyce AJ | Mov Disord |
| 23692359 | CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. | Zhu AZ | Addiction |
| 22048466 | Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. | King DP | Neuropsychopharmacology |
| 18571741 | Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. | Portugal GS | Behav Brain Res |
| 26351737 | Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use. | Melroy-Greif WE | Genes Brain Behav |
| 21229299 | Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers. | Sakoda LC | Cancer Causes Control |
| 22438921 | Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD. | Budulac SE | PLoS One |
| 23943838 | Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults. | Cannon DS | Nicotine Tob Res |
| 20581870 | From smoking to lung cancer: the CHRNA5/A3/B4 connection. | Improgo MR | Oncogene |
| 20700436 | Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. | Saccone NL | PLoS Genet |
| 28069549 | SNPs within CHRNA5-A3-B4 and CYP2A6/B6 are associated with smoking dependence but not with tobacco dependence treatment outcomes in the Czech population. | Hubacek JA | Gene |
| 23872218 | Functional characterization of SNPs in CHRNA3/B4 intergenic region associated with drug behaviors. | Flora AV | Brain Res |
| 23249876 | Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. | Bergen AW | Pharmacogenet Genomics |
| 21228559 | An exploratory study on the CHRNA3-CHRNA5-CHRNB4 cluster, smoking, and Parkinson's disease. | Gao J | Neurodegener Dis |
| 19706762 | The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. | Saccone NL | Cancer Res |
| 21862624 | Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. | Timofeeva MN | Cancer Epidemiol Biomarkers Prev |
| 25045619 | The Genetics, Neurogenetics and Pharmacogenetics of Addiction. | Demers CH | Curr Behav Neurosci Rep |
| 22042234 | Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. | Stephens SH | Behav Genet |
| 26010901 | Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking. | Tyndale RF | PLoS One |
| 21436384 | Genetic variability of smoking persistence in African Americans. | Hamidovic A | Cancer Prev Res (Phila) |
| 22291610 | A flexible Bayesian model for studying gene-environment interaction. | Yu K | PLoS Genet |
| 21949713 | Genetics of sputum gene expression in chronic obstructive pulmonary disease. | Qiu W | PLoS One |
| 18780872 | Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. | Liu P | J Natl Cancer Inst |
| 22241830 | Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits. | Broms U | Nicotine Tob Res |
| 25941207 | An Adolescent Substance Prevention Model Blocks the Effect of CHRNA5 Genotype on Smoking During High School. | Vandenbergh DJ | Nicotine Tob Res |
| 25471942 | Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism. | Wen L | Mol Neurobiol |
| 23875064 | Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study. | Hallfors J | Int J Mol Epidemiol Genet |
| 23024249 | Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions. | Harmey D | Nicotine Tob Res |
| 22884254 | Association of nicotine dependence susceptibility gene, CHRNA5, with Parkinson's disease age at onset: gene and smoking status interaction. | Greenbaum L | Parkinsonism Relat Disord |
| 23691092 | Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language. | Eicher JD | PLoS One |
| 20700147 | Nicotinic alpha5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms. | Smith RM | Eur J Hum Genet |
| 23255854 | A functional polymorphism in the CHRNA3 gene and risk of chronic obstructive pulmonary disease in a Korean population. | Lee JY | J Korean Med Sci |
| 27127891 | Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland. | Kita-Milczarska K | Med Sci Monit |
| 20584212 | Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. | Saccone NL | Genes Brain Behav |
| 21685187 | Genome-wide association study of smoking behaviours in patients with COPD. | Siedlinski M | Thorax |
| 26831765 | Association between two CHRNA3 variants and susceptibility of lung cancer: a meta-analysis. | Qu X | Sci Rep |
| 19628476 | Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. | Keskitalo K | Hum Mol Genet |
| 19029397 | Nicotinic receptor gene variants influence susceptibility to heavy smoking. | Stevens VL | Cancer Epidemiol Biomarkers Prev |
| 25233467 | Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma. | Tseng TS | PLoS One |