rs5921523

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0345 (7129/20608,GnomAD)
A==0278 (1050/3775,1000G)
A==0320 (1186/3708,TWINSUK)
A==0330 (952/2889,ALSPAC)
chrX:100224970 (GRCh38.p7) (Xq22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr XNC_000023.11:g.100224970A>C
GRCh37.p13 chr XNC_000023.10:g.99479968A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1003A=0.467C=0.533
1000GenomesAmericanSub524A=0.330C=0.670
1000GenomesEast AsianSub764A=0.160C=0.840
1000GenomesEuropeSub766A=0.250C=0.750
1000GenomesGlobalStudy-wide3775A=0.278C=0.722
1000GenomesSouth AsianSub718A=0.130C=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide2889A=0.330C=0.670
The Genome Aggregation DatabaseAfricanSub5777A=0.467C=0.533
The Genome Aggregation DatabaseAmericanSub616A=0.330C=0.670
The Genome Aggregation DatabaseEast AsianSub994A=0.200C=0.800
The Genome Aggregation DatabaseEuropeSub13036A=0.306C=0.693
The Genome Aggregation DatabaseGlobalStudy-wide20608A=0.345C=0.654
The Genome Aggregation DatabaseOtherSub185A=0.210C=0.790
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.320C=0.680
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs59215230.00019alcohol dependence20201924

eQTL of rs5921523 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5921523 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chrX9952941099529490E08149442
chrX9952966099529723E08149692
chrX9952977399529876E08149805