rs5922838

Homo sapiens
A>C / A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0197 (4059/20551,GnomAD)
G=0145 (537/3708,TWINSUK)
G=0152 (438/2889,ALSPAC)
chrX:83616187 (GRCh38.p7) (Xq21.1)
AD
GWASCatalog | GWASdb2
2   publication(s)
See rs on genome
0 Enhancer around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr XNC_000023.11:g.83616187A>C
GRCh38.p7 chr XNC_000023.11:g.83616187A>G
GRCh37.p13 chr XNC_000023.10:g.82871195A>C
GRCh37.p13 chr XNC_000023.10:g.82871195A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide2889A=0.848G=0.152
The Genome Aggregation DatabaseAfricanSub5873A=0.719G=0.280
The Genome Aggregation DatabaseAmericanSub577A=0.860G=0.14,
The Genome Aggregation DatabaseEast AsianSub987A=0.710G=0.29,
The Genome Aggregation DatabaseEuropeSub12933A=0.844G=0.155
The Genome Aggregation DatabaseGlobalStudy-wide20551A=0.802G=0.197
The Genome Aggregation DatabaseOtherSub181A=0.810G=0.19,
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.855G=0.145
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
22064162Genome-wide association study of comorbid depressive syndrome and alcohol dependence.Edwards ACPsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs59228385.00E-06alcohol dependence22064162
rs59228380.0007alcohol dependence20201924

eQTL of rs5922838 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5922838 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chrX5446630754467306E06715431
chrX5446735654467396E06716480
chrX5446755254467592E06716676
chrX5446630754467306E06815431
chrX5446735654467396E06816480
chrX5446755254467592E06816676
chrX5446630754467306E06915431
chrX5446735654467396E06916480
chrX5446755254467592E06916676
chrX5446630754467306E07015431
chrX5446735654467396E07016480
chrX5446755254467592E07016676
chrX5446630754467306E07115431
chrX5446735654467396E07116480
chrX5446755254467592E07116676
chrX5446630754467306E07215431
chrX5446735654467396E07216480
chrX5446755254467592E07216676
chrX5446630754467306E07315431
chrX5446735654467396E07316480
chrX5446755254467592E07316676
chrX5446630754467306E07415431
chrX5446735654467396E07416480
chrX5446755254467592E07416676
chrX5446630754467306E08115431
chrX5446735654467396E08116480
chrX5446630754467306E08215431
chrX5446735654467396E08216480
chrX5446755254467592E08216676