rs59317432

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0121 (3646/29940,GnomAD)
A=0130 (3810/29118,TOPMED)
A=0167 (834/5008,1000G)
A=0060 (231/3854,ALSPAC)
A=0048 (179/3708,TWINSUK)
chr8:100797434 (GRCh38.p7) (8q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.100797434G>A
GRCh37.p13 chr 8NC_000008.10:g.101809662G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.787A=0.213
1000GenomesAmericanSub694G=0.800A=0.200
1000GenomesEast AsianSub1008G=0.711A=0.289
1000GenomesEuropeSub1006G=0.948A=0.052
1000GenomesGlobalStudy-wide5008G=0.833A=0.167
1000GenomesSouth AsianSub978G=0.930A=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.940A=0.060
The Genome Aggregation DatabaseAfricanSub8702G=0.783A=0.217
The Genome Aggregation DatabaseAmericanSub838G=0.800A=0.200
The Genome Aggregation DatabaseEast AsianSub1616G=0.686A=0.314
The Genome Aggregation DatabaseEuropeSub18484G=0.942A=0.057
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.878A=0.121
The Genome Aggregation DatabaseOtherSub300G=0.950A=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.869A=0.130
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.952A=0.048
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs593174323.43E-05alcohol consumption23743675

eQTL of rs59317432 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs59317432 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-34616
chr8101847470101848214E06837808
chr8101762717101763214E071-46448
chr8101764400101764498E071-45164
chr8101764560101764751E071-44911
chr8101764770101764823E071-44839
chr8101803597101803661E072-6001
chr8101803758101804338E074-5324
chr8101804391101804510E074-5152
chr8101847470101848214E07437808
chr8101848259101848339E07438597
chr8101859230101859295E07449568
chr8101775773101775823E081-33839
chr8101775832101775882E081-33780
chr8101775951101776079E081-33583
chr8101803597101803661E081-6001
chr8101803758101804338E081-5324
chr8101804391101804510E081-5152
chr8101851627101851825E08141965
chr8101851845101851917E08142183
chr8101775334101775644E082-34018