rs5949232

Homo sapiens
G>A / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0467 (7502/16049,GnomAD)
A=0372 (1379/3708,TWINSUK)
A=0380 (1098/2889,ALSPAC)
chrX:24145170 (GRCh38.p7) (Xp22.11)
AD
GWASdb2
1   publication(s)
See rs on genome
30 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr XNC_000023.11:g.24145170G>A
GRCh38.p7 chr XNC_000023.11:g.24145170G>T
GRCh37.p13 chr XNC_000023.10:g.24163287G>A
GRCh37.p13 chr XNC_000023.10:g.24163287G>T
ZFX RefSeqGeneNG_021253.1:g.434G>A
ZFX RefSeqGeneNG_021253.1:g.434G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide2889G=0.620A=0.380
The Genome Aggregation DatabaseAfricanSub4631G=0.224A=0.776
The Genome Aggregation DatabaseAmericanSub466G=0.480A=0.520
The Genome Aggregation DatabaseEast AsianSub755G=0.390A=0.610
The Genome Aggregation DatabaseEuropeSub10048G=0.584A=0.415
The Genome Aggregation DatabaseGlobalStudy-wide16049G=0.467A=0.532
The Genome Aggregation DatabaseOtherSub149G=0.490A=0.510
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.628A=0.372
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs59492320.00085alcohol dependence20201924

eQTL of rs5949232 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs5949232 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chrX93897029389859E067-14115
chrX94306039431752E06726629
chrX94306039431752E06826629
chrX94352359435640E06831261
chrX94357379435915E06831763
chrX94359579436093E06831983
chrX94363729436607E06832398
chrX93980889398332E070-5642
chrX93984049398526E070-5448
chrX93986649398824E070-5150
chrX94058199406153E0701845
chrX94065139406563E0702539
chrX94306039431752E07026629
chrX94352359435640E07031261
chrX94304049430480E07126430
chrX94352359435640E07131261
chrX94357379435915E07131763
chrX94359579436093E07131983
chrX94304049430480E07226430
chrX94306039431752E07326629
chrX94304049430480E07426430
chrX93691049369433E081-34541
chrX93846939384948E081-19026
chrX93849629385024E081-18950
chrX93850949385248E081-18726
chrX94298239429973E08125849
chrX94300329430118E08126058
chrX94304049430480E08126430
chrX94306039431752E08126629
chrX93892819389379E082-14595









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chrX94318599434793E06727885
chrX94318599434793E06827885
chrX94318599434793E06927885
chrX94318599434793E07027885
chrX94318599434793E07127885
chrX94318599434793E07227885
chrX94318599434793E07327885
chrX94318599434793E08227885