SNP Detail Info-rs59551326

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0102 (3070/29988,GnomAD)
G=0104 (3041/29118,TOPMED)
G=0071 (356/5008,1000G)
G=0094 (363/3854,ALSPAC)
G=0098 (364/3708,TWINSUK)

Position: chr21:25384656 (GRCh38.p7) (21q21.2)

Phenotype: AD

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 21	NC_000021.9:g.25384656A>G
GRCh37.p13 chr 21	NC_000021.8:g.26756969A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.874	G=0.126
1000Genomes	American	Sub	694	A=0.960	G=0.040
1000Genomes	East Asian	Sub	1008	A=0.984	G=0.016
1000Genomes	Europe	Sub	1006	A=0.909	G=0.091
1000Genomes	Global	Study-wide	5008	A=0.929	G=0.071
1000Genomes	South Asian	Sub	978	A=0.950	G=0.050
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.906	G=0.094
The Genome Aggregation Database	African	Sub	8728	A=0.857	G=0.143
The Genome Aggregation Database	American	Sub	836	A=0.970	G=0.030
The Genome Aggregation Database	East Asian	Sub	1622	A=0.967	G=0.033
The Genome Aggregation Database	Europe	Sub	18500	A=0.906	G=0.093
The Genome Aggregation Database	Global	Study-wide	29988	A=0.897	G=0.102
The Genome Aggregation Database	Other	Sub	302	A=0.940	G=0.060
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.895	G=0.104
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.902	G=0.098

PMID	Title	Author	Journal
24166409	Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.	Gelernter J	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs59551326	9.00E-07	alcohol dependence	24166409
rs59551326	5.00E-06	alcohol dependence	24166409

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs59551326