rs59677118

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0088 (2634/29628,GnomAD)
A=0058 (1699/29118,TOPMED)
A=0083 (417/5008,1000G)
A=0088 (339/3854,ALSPAC)
A=0094 (349/3708,TWINSUK)
chr9:14441679 (GRCh38.p7) (9p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
114 Enhancers around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.14441679G>A
GRCh37.p13 chr 9NC_000009.11:g.14441677G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.962A=0.038
1000GenomesAmericanSub694G=0.950A=0.050
1000GenomesEast AsianSub1008G=0.933A=0.067
1000GenomesEuropeSub1006G=0.895A=0.105
1000GenomesGlobalStudy-wide5008G=0.917A=0.083
1000GenomesSouth AsianSub978G=0.840A=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.912A=0.088
The Genome Aggregation DatabaseAfricanSub8666G=0.955A=0.045
The Genome Aggregation DatabaseAmericanSub830G=0.960A=0.040
The Genome Aggregation DatabaseEast AsianSub1618G=0.925A=0.075
The Genome Aggregation DatabaseEuropeSub18212G=0.885A=0.114
The Genome Aggregation DatabaseGlobalStudy-wide29628G=0.911A=0.088
The Genome Aggregation DatabaseOtherSub302G=0.960A=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.941A=0.058
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.906A=0.094
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs596771181E-06alcohol consumption23743675

eQTL of rs59677118 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs59677118 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr91439820514398468E067-43209
chr91439853814398778E067-42899
chr91439885114398934E067-42743
chr91442857914429399E067-12278
chr91439511114395272E068-46405
chr91439629014396611E068-45066
chr91439667014396797E068-44880
chr91439687814397076E068-44601
chr91439713914397189E068-44488
chr91439784514398061E068-43616
chr91439820514398468E068-43209
chr91439853814398778E068-42899
chr91442857914429399E068-12278
chr91443237614434458E068-7219
chr91443702914438420E068-3257
chr91448279514483182E06841118
chr91439687814397076E069-44601
chr91439713914397189E069-44488
chr91439784514398061E069-43616
chr91439820514398468E069-43209
chr91439853814398778E069-42899
chr91439885114398934E069-42743
chr91439924314399327E069-42350
chr91439962814399678E069-41999
chr91440120514401273E069-40404
chr91442857914429399E069-12278
chr91443702914438420E069-3257
chr91439511114395272E070-46405
chr91439667014396797E070-44880
chr91439687814397076E070-44601
chr91439713914397189E070-44488
chr91440269914402830E070-38847
chr91441821614419877E070-21800
chr91442823514428363E070-13314
chr91442837614428535E070-13142
chr91442857914429399E070-12278
chr91443197114432147E070-9530
chr91443222014432270E070-9407
chr91443237614434458E070-7219
chr91443702914438420E070-3257
chr91443843214438587E070-3090
chr91443867514438965E070-2712
chr91443930014439364E070-2313
chr91444120214441416E070-261
chr91446540014466861E07023723
chr91448279514483182E07041118
chr91439511114395272E071-46405
chr91439667014396797E071-44880
chr91439687814397076E071-44601
chr91439713914397189E071-44488
chr91439784514398061E071-43616
chr91439820514398468E071-43209
chr91440120514401273E071-40404
chr91443633814436638E071-5039
chr91443665914436771E071-4906
chr91443681614436860E071-4817
chr91443702914438420E071-3257
chr91439784514398061E072-43616
chr91439820514398468E072-43209
chr91439885114398934E072-42743
chr91440010114401196E072-40481
chr91440120514401273E072-40404
chr91442857914429399E072-12278
chr91443702914438420E073-3257
chr91439687814397076E074-44601
chr91439713914397189E074-44488
chr91439784514398061E074-43616
chr91439820514398468E074-43209
chr91439885114398934E074-42743
chr91439962814399678E074-41999
chr91440120514401273E074-40404
chr91441821614419877E074-21800
chr91442837614428535E074-13142
chr91442857914429399E074-12278
chr91447889714479053E07437220
chr91447934314479421E07437666
chr91439629014396611E081-45066
chr91439667014396797E081-44880
chr91440010114401196E081-40481
chr91440120514401273E081-40404
chr91440130814402453E081-39224
chr91440269914402830E081-38847
chr91440522514405275E081-36402
chr91441821614419877E081-21800
chr91442857914429399E081-12278
chr91443702914438420E081-3257
chr91443843214438587E081-3090
chr91443867514438965E081-2712
chr91444120214441416E081-261
chr91445060714450669E0818930
chr91445086414451049E0819187
chr91445109114451143E0819414
chr91445256014452893E08110883
chr91445300114453068E08111324
chr91445324014453586E08111563
chr91439511114395272E082-46405
chr91439667014396797E082-44880
chr91439687814397076E082-44601
chr91439713914397189E082-44488
chr91440269914402830E082-38847
chr91443447514434610E082-7067
chr91443466014434801E082-6876
chr91443702914438420E082-3257
chr91443843214438587E082-3090
chr91443867514438965E082-2712
chr91443930014439364E082-2313
chr91444009214440405E082-1272
chr91444044314440497E082-1180
chr91444057014440652E082-1025
chr91444068914440739E082-938
chr91444077614440826E082-851
chr91444106714441121E082-556
chr91444120214441416E082-261
chr91445324014453586E08211563










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr91439536514395413E068-46264
chr91439542014395689E068-45988
chr91439575314396067E068-45610
chr91439542014395689E069-45988
chr91439575314396067E069-45610
chr91439536514395413E070-46264
chr91439542014395689E070-45988
chr91439575314396067E070-45610
chr91439536514395413E071-46264
chr91439542014395689E071-45988
chr91439575314396067E071-45610
chr91439536514395413E072-46264
chr91439542014395689E072-45988
chr91439575314396067E072-45610
chr91439575314396067E074-45610