rs6014619

Homo sapiens
C>G
LOC105372680 : 2KB Upstream Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0423 (12678/29914,GnomAD)
C==0453 (13190/29118,TOPMED)
C==0415 (2080/5008,1000G)
C==0349 (1344/3854,ALSPAC)
C==0337 (1250/3708,TWINSUK)
chr20:56171081 (GRCh38.p7) (20q13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.56171081C>G
GRCh37.p13 chr 20NC_000020.10:g.54746137C>G

Gene: LOC105372680, uncharacterized LOC105372680(minus strand): 2KB Upstream Variant

Molecule type Change Amino acid[Codon] SO Term
LOC105372680 transcript variant X2XR_936893.2:n.N/AUpstream Transcript Variant
LOC105372680 transcript variant X1XR_001754685.1:n.N/AN/A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.659G=0.341
1000GenomesAmericanSub694C=0.280G=0.720
1000GenomesEast AsianSub1008C=0.344G=0.656
1000GenomesEuropeSub1006C=0.359G=0.641
1000GenomesGlobalStudy-wide5008C=0.415G=0.585
1000GenomesSouth AsianSub978C=0.310G=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.349G=0.651
The Genome Aggregation DatabaseAfricanSub8696C=0.599G=0.401
The Genome Aggregation DatabaseAmericanSub838C=0.260G=0.740
The Genome Aggregation DatabaseEast AsianSub1620C=0.333G=0.667
The Genome Aggregation DatabaseEuropeSub18458C=0.359G=0.640
The Genome Aggregation DatabaseGlobalStudy-wide29914C=0.423G=0.576
The Genome Aggregation DatabaseOtherSub302C=0.240G=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.453G=0.547
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.337G=0.663
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs60146190.000533alcohol dependence21314694

eQTL of rs6014619 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6014619 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr205474426554744521E070-1616
chr205476234454762512E07016207
chr205476257954763244E07016442
chr205476340054763520E07017263
chr205476353254763582E07017395
chr205476257954763244E08116442
chr205476340054763520E08117263
chr205476353254763582E08117395
chr205476340054763520E08217263
chr205476353254763582E08217395