rs6018477

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0221 (6600/29844,GnomAD)
C=0275 (8016/29118,TOPMED)
C=0266 (1333/5008,1000G)
C=0165 (636/3854,ALSPAC)
C=0170 (630/3708,TWINSUK)
chr20:47431079 (GRCh38.p7) (20q13.12)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.47431079A>C
GRCh37.p13 chr 20NC_000020.10:g.46059823A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.657C=0.343
1000GenomesAmericanSub694A=0.660C=0.340
1000GenomesEast AsianSub1008A=0.748C=0.252
1000GenomesEuropeSub1006A=0.828C=0.172
1000GenomesGlobalStudy-wide5008A=0.734C=0.266
1000GenomesSouth AsianSub978A=0.780C=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.835C=0.165
The Genome Aggregation DatabaseAfricanSub8668A=0.680C=0.320
The Genome Aggregation DatabaseAmericanSub830A=0.630C=0.370
The Genome Aggregation DatabaseEast AsianSub1612A=0.756C=0.244
The Genome Aggregation DatabaseEuropeSub18432A=0.834C=0.165
The Genome Aggregation DatabaseGlobalStudy-wide29844A=0.778C=0.221
The Genome Aggregation DatabaseOtherSub302A=0.720C=0.280
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.724C=0.275
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.830C=0.170
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs60184770.000449alcohol dependence20201924

eQTL of rs6018477 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6018477 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr204601243646013353E067-46470
chr204601154946012070E068-47753
chr204601243646013353E069-46470
chr204601243646013353E070-46470
chr204602692646027030E070-32793
chr204602714046027221E070-32602
chr204601243646013353E073-46470
chr204601243646013353E074-46470
chr204601243646013353E081-46470
chr204602692646027030E081-32793
chr204602714046027221E081-32602
chr204602760246027652E081-32171
chr204601243646013353E082-46470