rs60349741

Homo sapiens
A>C / A>T
KCNC1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0018 (549/29942,GnomAD)
C=0021 (105/5008,1000G)
C=0001 (4/3854,ALSPAC)
C=0001 (3/3708,TWINSUK)
chr11:17774564 (GRCh38.p7) (11p15.1)
OD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.17774564A>C
GRCh38.p7 chr 11NC_000011.10:g.17774564A>T
GRCh37.p13 chr 11NC_000011.9:g.17796111A>C
GRCh37.p13 chr 11NC_000011.9:g.17796111A>T
KCNC1 RefSeqGeneNG_041827.1:g.43617A>C
KCNC1 RefSeqGeneNG_041827.1:g.43617A>T

Gene: KCNC1, potassium voltage-gated channel subfamily C member 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KCNC1 transcript variant 1NM_001112741.1:c.N/AIntron Variant
KCNC1 transcript variant 2NM_004976.4:c.N/A3 Prime UTR Variant
KCNC1 transcript variant X1XM_011520080.2:c.N/AIntron Variant
KCNC1 transcript variant X2XR_001747861.1:n.N/AIntron Variant
KCNC1 transcript variant X1XR_930866.2:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.927C=0.073
1000GenomesAmericanSub694A=0.990C=0.010
1000GenomesEast AsianSub1008A=1.000C=0.000
1000GenomesEuropeSub1006A=0.999C=0.001
1000GenomesGlobalStudy-wide5008A=0.979C=0.021
1000GenomesSouth AsianSub978A=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.999C=0.001
The Genome Aggregation DatabaseAfricanSub8708A=0.941C=0.059
The Genome Aggregation DatabaseAmericanSub838A=0.990C=0.010
The Genome Aggregation DatabaseEast AsianSub1622A=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18472A=0.999C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29942A=0.981C=0.018
The Genome Aggregation DatabaseOtherSub302A=0.970C=0.030
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.999C=0.001
PMID Title Author Journal
24143882Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.Gelernter JBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs603497415E-07Opioid sensitivity24143882

eQTL of rs60349741 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs60349741 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.