rs6047255

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0476 (14258/29944,GnomAD)
G=0456 (13296/29118,TOPMED)
A==0482 (2414/5008,1000G)
A==0392 (1510/3854,ALSPAC)
A==0362 (1344/3708,TWINSUK)
chr20:21115295 (GRCh38.p7) (20p11.23)
AD
GWASdb2
1   publication(s)
See rs on genome
58 Enhancers around
40 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.21115295A>G
GRCh37.p13 chr 20NC_000020.10:g.21095936A>G
RPL24P2 pseudogeneNG_001003.5:g.715A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.790G=0.210
1000GenomesAmericanSub694A=0.440G=0.560
1000GenomesEast AsianSub1008A=0.439G=0.561
1000GenomesEuropeSub1006A=0.376G=0.624
1000GenomesGlobalStudy-wide5008A=0.482G=0.518
1000GenomesSouth AsianSub978A=0.250G=0.750
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.392G=0.608
The Genome Aggregation DatabaseAfricanSub8712A=0.718G=0.282
The Genome Aggregation DatabaseAmericanSub838A=0.490G=0.510
The Genome Aggregation DatabaseEast AsianSub1614A=0.433G=0.567
The Genome Aggregation DatabaseEuropeSub18478A=0.367G=0.632
The Genome Aggregation DatabaseGlobalStudy-wide29944A=0.476G=0.523
The Genome Aggregation DatabaseOtherSub302A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.543G=0.456
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.362G=0.638
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs60472557.96E-05alcohol dependence21703634

eQTL of rs6047255 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6047255 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr202107062221071622E067-24314
chr202107166821071778E067-24158
chr202113552121135574E06739585
chr202107000921070365E068-25571
chr202107992321080061E068-15875
chr202110919021109248E06813254
chr202114244321142493E06846507
chr202114267521143793E06846739
chr202107000921070365E069-25571
chr202107166821071778E069-24158
chr202107968721079814E069-16122
chr202107992321080061E069-15875
chr202110789321108272E06911957
chr202112269621122746E06926760
chr202112815421128216E06932218
chr202112832521128521E06932389
chr202112856621128646E06932630
chr202112865721128766E06932721
chr202113241421132471E06936478
chr202113251821132775E06936582
chr202105535221055402E070-40534
chr202105559921055843E070-40093
chr202105636021056410E070-39526
chr202107000921070365E070-25571
chr202107045721070571E070-25365
chr202107166821071778E070-24158
chr202107690921077188E070-18748
chr202107719721077399E070-18537
chr202107901821079068E070-16868
chr202107918121079267E070-16669
chr202107940521079515E070-16421
chr202107956621079628E070-16308
chr202107968721079814E070-16122
chr202107992321080061E070-15875
chr202113241421132471E07136478
chr202113251821132775E07136582
chr202107062221071622E072-24314
chr202107166821071778E072-24158
chr202112832521128521E07232389
chr202112856621128646E07232630
chr202112865721128766E07232721
chr202113199721132099E07236061
chr202113241421132471E07236478
chr202113251821132775E07236582
chr202107166821071778E074-24158
chr202107182621071886E074-24050
chr202107199721072077E074-23859
chr202110789321108272E07411957
chr202112269621122746E07426760
chr202112856621128646E07432630
chr202112865721128766E07432721
chr202113241421132471E07436478
chr202113251821132775E07436582
chr202113282821132868E07436892
chr202113510921135159E07439173
chr202114073421140799E07444798
chr202107166821071778E081-24158
chr202107062221071622E082-24314









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr202108036821081959E067-13977
chr202108200521084613E067-11323
chr202110578621107756E0679850
chr202108036821081959E068-13977
chr202108200521084613E068-11323
chr202108598321086527E068-9409
chr202108658121086974E068-8962
chr202110578621107756E0689850
chr202108036821081959E069-13977
chr202108200521084613E069-11323
chr202108598321086527E069-9409
chr202108658121086974E069-8962
chr202108707021087128E069-8808
chr202110578621107756E0699850
chr202110578621107756E0709850
chr202108036821081959E071-13977
chr202108598321086527E071-9409
chr202108658121086974E071-8962
chr202110578621107756E0719850
chr202108036821081959E072-13977
chr202108200521084613E072-11323
chr202108598321086527E072-9409
chr202108658121086974E072-8962
chr202108707021087128E072-8808
chr202110578621107756E0729850
chr202108036821081959E073-13977
chr202108200521084613E073-11323
chr202108598321086527E073-9409
chr202108658121086974E073-8962
chr202110578621107756E0739850
chr202108036821081959E074-13977
chr202108200521084613E074-11323
chr202108598321086527E074-9409
chr202108658121086974E074-8962
chr202110578621107756E0749850
chr202108036821081959E082-13977
chr202108200521084613E082-11323
chr202108598321086527E082-9409
chr202108658121086974E082-8962
chr202110578621107756E0829850