rs6082329

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0493 (14367/29118,TOPMED)
A==0425 (12061/28368,GnomAD)
A==0450 (2254/5008,1000G)
A==0388 (1496/3854,ALSPAC)
A==0360 (1335/3708,TWINSUK)
chr20:21119497 (GRCh38.p7) (20p11.23)
AD
GWASdb2
1   publication(s)
See rs on genome
58 Enhancers around
40 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.21119497A>C
GRCh37.p13 chr 20NC_000020.10:g.21100138A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.679C=0.321
1000GenomesAmericanSub694A=0.430C=0.570
1000GenomesEast AsianSub1008A=0.441C=0.559
1000GenomesEuropeSub1006A=0.376C=0.624
1000GenomesGlobalStudy-wide5008A=0.450C=0.550
1000GenomesSouth AsianSub978A=0.240C=0.760
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.388C=0.612
The Genome Aggregation DatabaseAfricanSub7966A=0.590C=0.410
The Genome Aggregation DatabaseAmericanSub814A=0.470C=0.530
The Genome Aggregation DatabaseEast AsianSub1520A=0.404C=0.596
The Genome Aggregation DatabaseEuropeSub17770A=0.352C=0.647
The Genome Aggregation DatabaseGlobalStudy-wide28368A=0.425C=0.574
The Genome Aggregation DatabaseOtherSub298A=0.370C=0.630
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.493C=0.506
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.360C=0.640
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs60823297.95E-05alcohol dependence21703634

eQTL of rs6082329 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6082329 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr202107062221071622E067-28516
chr202107166821071778E067-28360
chr202113552121135574E06735383
chr202107000921070365E068-29773
chr202107992321080061E068-20077
chr202110919021109248E0689052
chr202114244321142493E06842305
chr202114267521143793E06842537
chr202107000921070365E069-29773
chr202107166821071778E069-28360
chr202107968721079814E069-20324
chr202107992321080061E069-20077
chr202110789321108272E0697755
chr202112269621122746E06922558
chr202112815421128216E06928016
chr202112832521128521E06928187
chr202112856621128646E06928428
chr202112865721128766E06928519
chr202113241421132471E06932276
chr202113251821132775E06932380
chr202105535221055402E070-44736
chr202105559921055843E070-44295
chr202105636021056410E070-43728
chr202107000921070365E070-29773
chr202107045721070571E070-29567
chr202107166821071778E070-28360
chr202107690921077188E070-22950
chr202107719721077399E070-22739
chr202107901821079068E070-21070
chr202107918121079267E070-20871
chr202107940521079515E070-20623
chr202107956621079628E070-20510
chr202107968721079814E070-20324
chr202107992321080061E070-20077
chr202113241421132471E07132276
chr202113251821132775E07132380
chr202107062221071622E072-28516
chr202107166821071778E072-28360
chr202112832521128521E07228187
chr202112856621128646E07228428
chr202112865721128766E07228519
chr202113199721132099E07231859
chr202113241421132471E07232276
chr202113251821132775E07232380
chr202107166821071778E074-28360
chr202107182621071886E074-28252
chr202107199721072077E074-28061
chr202110789321108272E0747755
chr202112269621122746E07422558
chr202112856621128646E07428428
chr202112865721128766E07428519
chr202113241421132471E07432276
chr202113251821132775E07432380
chr202113282821132868E07432690
chr202113510921135159E07434971
chr202114073421140799E07440596
chr202107166821071778E081-28360
chr202107062221071622E082-28516









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr202108036821081959E067-18179
chr202108200521084613E067-15525
chr202110578621107756E0675648
chr202108036821081959E068-18179
chr202108200521084613E068-15525
chr202108598321086527E068-13611
chr202108658121086974E068-13164
chr202110578621107756E0685648
chr202108036821081959E069-18179
chr202108200521084613E069-15525
chr202108598321086527E069-13611
chr202108658121086974E069-13164
chr202108707021087128E069-13010
chr202110578621107756E0695648
chr202110578621107756E0705648
chr202108036821081959E071-18179
chr202108598321086527E071-13611
chr202108658121086974E071-13164
chr202110578621107756E0715648
chr202108036821081959E072-18179
chr202108200521084613E072-15525
chr202108598321086527E072-13611
chr202108658121086974E072-13164
chr202108707021087128E072-13010
chr202110578621107756E0725648
chr202108036821081959E073-18179
chr202108200521084613E073-15525
chr202108598321086527E073-13611
chr202108658121086974E073-13164
chr202110578621107756E0735648
chr202108036821081959E074-18179
chr202108200521084613E074-15525
chr202108598321086527E074-13611
chr202108658121086974E074-13164
chr202110578621107756E0745648
chr202108036821081959E082-18179
chr202108200521084613E082-15525
chr202108598321086527E082-13611
chr202108658121086974E082-13164
chr202110578621107756E0825648