rs6099690

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0331 (9924/29914,GnomAD)
T==0362 (10541/29118,TOPMED)
T==0266 (1333/5008,1000G)
T==0263 (1013/3854,ALSPAC)
T==0278 (1032/3708,TWINSUK)
chr20:57635380 (GRCh38.p7) (20q13.31)
ND
GWASdb2
1   publication(s)
See rs on genome
255 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.57635380T>C
GRCh37.p13 chr 20NC_000020.10:g.56210436T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.568C=0.432
1000GenomesAmericanSub694T=0.210C=0.790
1000GenomesEast AsianSub1008T=0.011C=0.989
1000GenomesEuropeSub1006T=0.301C=0.699
1000GenomesGlobalStudy-wide5008T=0.266C=0.734
1000GenomesSouth AsianSub978T=0.120C=0.880
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.263C=0.737
The Genome Aggregation DatabaseAfricanSub8704T=0.526C=0.474
The Genome Aggregation DatabaseAmericanSub838T=0.160C=0.840
The Genome Aggregation DatabaseEast AsianSub1620T=0.012C=0.988
The Genome Aggregation DatabaseEuropeSub18450T=0.277C=0.722
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.331C=0.668
The Genome Aggregation DatabaseOtherSub302T=0.260C=0.740
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.362C=0.638
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.278C=0.722
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs60996900.000701nicotine dependence17158188

eQTL of rs6099690 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6099690 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr205623579656236038E06725360
chr205623685056237049E06726414
chr205623714056237724E06726704
chr205623774956237873E06727313
chr205623787656237966E06727440
chr205623817056238220E06727734
chr205623832556238375E06727889
chr205624779056247907E06737354
chr205624795356248057E06737517
chr205616128456161350E068-49086
chr205618764156187691E068-22745
chr205623235056233237E06821914
chr205623356756233663E06823131
chr205623371156233842E06823275
chr205623396356234132E06823527
chr205623414256234247E06823706
chr205623430456234374E06823868
chr205623439456234591E06823958
chr205623621456236693E06825778
chr205623685056237049E06826414
chr205623714056237724E06826704
chr205623774956237873E06827313
chr205623787656237966E06827440
chr205623817056238220E06827734
chr205623832556238375E06827889
chr205624308156243337E06832645
chr205624334856243432E06832912
chr205624345256243719E06833016
chr205624376656243826E06833330
chr205624678756247746E06836351
chr205624779056247907E06837354
chr205624795356248057E06837517
chr205624836656248455E06837930
chr205624855956248639E06838123
chr205624873756248924E06838301
chr205624910556249195E06838669
chr205624934656249396E06838910
chr205625047856250518E06840042
chr205625120756251263E06840771
chr205625134256251480E06840906
chr205625148556251616E06841049
chr205625166756251975E06841231
chr205625214056252275E06841704
chr205625228156252722E06841845
chr205625291556252965E06842479
chr205625317556253225E06842739
chr205625324456253333E06842808
chr205625345356253984E06843017
chr205625612556256768E06845689
chr205625680456256954E06846368
chr205625701656257359E06846580
chr205625738256257518E06846946
chr205625757456258663E06847138
chr205625866656259270E06848230
chr205625937356259576E06848937
chr205618715156187221E069-23215
chr205618722256187313E069-23123
chr205618751456187637E069-22799
chr205618764156187691E069-22745
chr205623356756233663E06923131
chr205623621456236693E06925778
chr205623685056237049E06926414
chr205623714056237724E06926704
chr205623774956237873E06927313
chr205623787656237966E06927440
chr205623817056238220E06927734
chr205623832556238375E06927889
chr205624678756247746E06936351
chr205625345356253984E06943017
chr205623469056234763E07024254
chr205623508856235150E07024652
chr205623579656236038E07025360
chr205623621456236693E07025778
chr205623685056237049E07026414
chr205623714056237724E07026704
chr205623774956237873E07027313
chr205623787656237966E07027440
chr205623817056238220E07027734
chr205623832556238375E07027889
chr205623858756238648E07028151
chr205624130456241415E07030868
chr205624143156241481E07030995
chr205624161656241678E07031180
chr205624179456241866E07031358
chr205624187056241914E07031434
chr205624204856242197E07031612
chr205624219856242272E07031762
chr205624231756242414E07031881
chr205624257956242824E07032143
chr205624308156243337E07032645
chr205624334856243432E07032912
chr205624345256243719E07033016
chr205624376656243826E07033330
chr205624493556245055E07034499
chr205624535356245476E07034917
chr205624552556245605E07035089
chr205624565656245738E07035220
chr205624587456245924E07035438
chr205624599356246068E07035557
chr205624836656248455E07037930
chr205624855956248639E07038123
chr205624873756248924E07038301
chr205624910556249195E07038669
chr205624934656249396E07038910
chr205624960056249650E07039164
chr205624979556249889E07039359
chr205625214056252275E07041704
chr205625228156252722E07041845
chr205625324456253333E07042808
chr205625345356253984E07043017
chr205625612556256768E07045689
chr205625680456256954E07046368
chr205625701656257359E07046580
chr205625738256257518E07046946
chr205625757456258663E07047138
chr205618655856186713E071-23723
chr205618671556186765E071-23671
chr205618678256186873E071-23563
chr205618715156187221E071-23215
chr205620266756202811E071-7625
chr205623579656236038E07125360
chr205623621456236693E07125778
chr205623685056237049E07126414
chr205623714056237724E07126704
chr205623774956237873E07127313
chr205623787656237966E07127440
chr205623817056238220E07127734
chr205623832556238375E07127889
chr205623858756238648E07128151
chr205624779056247907E07137354
chr205624795356248057E07137517
chr205625047856250518E07140042
chr205625059656250729E07140160
chr205625089056251051E07140454
chr205625120756251263E07140771
chr205625134256251480E07140906
chr205625148556251616E07141049
chr205625166756251975E07141231
chr205625214056252275E07141704
chr205625228156252722E07141845
chr205625291556252965E07142479
chr205625317556253225E07142739
chr205625324456253333E07142808
chr205625345356253984E07143017
chr205625403056254161E07143594
chr205625423456254594E07143798
chr205625757456258663E07147138
chr205625866656259270E07148230
chr205625937356259576E07148937
chr205618715156187221E072-23215
chr205618722256187313E072-23123
chr205618751456187637E072-22799
chr205618764156187691E072-22745
chr205623579656236038E07225360
chr205623685056237049E07226414
chr205623714056237724E07226704
chr205623774956237873E07227313
chr205623787656237966E07227440
chr205623817056238220E07227734
chr205624678756247746E07236351
chr205624779056247907E07237354
chr205624795356248057E07237517
chr205624836656248455E07237930
chr205624855956248639E07238123
chr205625345356253984E07243017
chr205623579656236038E07325360
chr205623621456236693E07325778
chr205623685056237049E07326414
chr205623714056237724E07326704
chr205624779056247907E07337354
chr205624795356248057E07337517
chr205624960056249650E07339164
chr205625166756251975E07341231
chr205625214056252275E07341704
chr205625680456256954E07346368
chr205625701656257359E07346580
chr205625866656259270E07348230
chr205625937356259576E07348937
chr205618678256186873E074-23563
chr205618715156187221E074-23215
chr205618722256187313E074-23123
chr205618751456187637E074-22799
chr205618764156187691E074-22745
chr205620266756202811E074-7625
chr205623579656236038E07425360
chr205623621456236693E07425778
chr205623685056237049E07426414
chr205623714056237724E07426704
chr205623774956237873E07427313
chr205623787656237966E07427440
chr205623817056238220E07427734
chr205623832556238375E07427889
chr205623858756238648E07428151
chr205623900556239076E07428569
chr205624308156243337E07432645
chr205624334856243432E07432912
chr205624678756247746E07436351
chr205624779056247907E07437354
chr205624795356248057E07437517
chr205624836656248455E07437930
chr205625291556252965E07442479
chr205625345356253984E07443017
chr205625459656256097E07444160
chr205625701656257359E07446580
chr205625738256257518E07446946
chr205625937356259576E07448937
chr205617177556171845E081-38591
chr205617184956172588E081-37848
chr205620266756202811E081-7625
chr205623579656236038E08125360
chr205623621456236693E08125778
chr205623685056237049E08126414
chr205624231756242414E08131881
chr205624257956242824E08132143
chr205624308156243337E08132645
chr205624552556245605E08135089
chr205624565656245738E08135220
chr205624587456245924E08135438
chr205624599356246068E08135557
chr205624612956246213E08135693
chr205624650756246638E08136071
chr205624678756247746E08136351
chr205624779056247907E08137354
chr205624795356248057E08137517
chr205624836656248455E08137930
chr205624855956248639E08138123
chr205624873756248924E08138301
chr205625214056252275E08141704
chr205625228156252722E08141845
chr205625324456253333E08142808
chr205625345356253984E08143017
chr205625612556256768E08145689
chr205625680456256954E08146368
chr205625701656257359E08146580
chr205625738256257518E08146946
chr205625757456258663E08147138
chr205625866656259270E08148230
chr205625937356259576E08148937
chr205623469056234763E08224254
chr205624493556245055E08234499
chr205624535356245476E08234917
chr205624552556245605E08235089
chr205624565656245738E08235220
chr205624650756246638E08236071
chr205624795356248057E08237517
chr205624836656248455E08237930
chr205624855956248639E08238123
chr205625317556253225E08242739
chr205625324456253333E08242808
chr205625345356253984E08243017
chr205625403056254161E08243594
chr205625423456254594E08243798
chr205625757456258663E08247138
chr205625866656259270E08248230
chr205625937356259576E08248937