rs6102185

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0314 (9384/29856,GnomAD)
G==0320 (9345/29118,TOPMED)
G==0337 (1686/5008,1000G)
G==0360 (1387/3854,ALSPAC)
G==0363 (1345/3708,TWINSUK)
chr20:40849893 (GRCh38.p7) (20q12)
ND
GWASdb2
1   publication(s)
See rs on genome
45 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.40849893G>A
GRCh37.p13 chr 20NC_000020.10:g.39478533G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.202A=0.798
1000GenomesAmericanSub694G=0.440A=0.560
1000GenomesEast AsianSub1008G=0.412A=0.588
1000GenomesEuropeSub1006G=0.375A=0.625
1000GenomesGlobalStudy-wide5008G=0.337A=0.663
1000GenomesSouth AsianSub978G=0.330A=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.360A=0.640
The Genome Aggregation DatabaseAfricanSub8688G=0.219A=0.781
The Genome Aggregation DatabaseAmericanSub836G=0.450A=0.550
The Genome Aggregation DatabaseEast AsianSub1604G=0.376A=0.624
The Genome Aggregation DatabaseEuropeSub18426G=0.348A=0.651
The Genome Aggregation DatabaseGlobalStudy-wide29856G=0.314A=0.685
The Genome Aggregation DatabaseOtherSub302G=0.260A=0.740
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.320A=0.679
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.363A=0.637
PMID Title Author Journal
22377092ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies.Wang KSDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs61021856.14E-05nicotine dependence (smoking)22377092

eQTL of rs6102185 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6102185 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr203949688839497087E06818355
chr203949712439498096E06818591
chr203949812539498570E06819592
chr203949712439498096E06918591
chr203945907639459126E070-19407
chr203945961839459658E070-18875
chr203945970539459846E070-18687
chr203945989339459987E070-18546
chr203946033339460387E070-18146
chr203946058039460634E070-17899
chr203947184739471897E070-6636
chr203947201639472188E070-6345
chr203947232039472415E070-6118
chr203947249239472542E070-5991
chr203947267239472722E070-5811
chr203947274639472796E070-5737
chr203947284039472898E070-5635
chr203947298339473256E070-5277
chr203947331639473368E070-5165
chr203947342639473637E070-4896
chr203947658639476673E070-1860
chr203947667439476741E070-1792
chr203947704439477608E070-925
chr203947820639478409E070-124
chr203947849639478546E0700
chr203947963139480145E0701098
chr203948704539487136E0708512
chr203948716639487470E0708633
chr203948768339487767E0709150
chr203948781539487911E0709282
chr203948794239488027E0709409
chr203948811039488217E0709577
chr203949041639490583E07011883
chr203949060039490797E07012067
chr203947232039472415E081-6118
chr203947249239472542E081-5991
chr203947267239472722E081-5811
chr203947274639472796E081-5737
chr203947284039472898E081-5635
chr203947298339473256E081-5277
chr203947704439477608E081-925
chr203947963139480145E0811098
chr203948019839480346E0811665
chr203948052939480583E0811996
chr203948685739486978E0828324