rs6129784

Homo sapiens
T>C
ZHX3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0209 (6258/29898,GnomAD)
C=0211 (6157/29118,TOPMED)
C=0240 (1201/5008,1000G)
C=0210 (811/3854,ALSPAC)
C=0216 (802/3708,TWINSUK)
chr20:41256889 (GRCh38.p7) (20q12)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.41256889T>C
GRCh37.p13 chr 20NC_000020.10:g.39885529T>C
ZHX3 RefSeqGeneNG_046923.1:g.65730A>G

Gene: ZHX3, zinc fingers and homeoboxes 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ZHX3 transcriptNM_015035.3:c.N/AIntron Variant
ZHX3 transcript variant X19XM_005260341.3:c.N/AIntron Variant
ZHX3 transcript variant X1XM_005260343.4:c.N/AIntron Variant
ZHX3 transcript variant X12XM_006723748.3:c.N/AIntron Variant
ZHX3 transcript variant X3XM_011528701.2:c.N/AIntron Variant
ZHX3 transcript variant X5XM_011528702.2:c.N/AIntron Variant
ZHX3 transcript variant X7XM_011528703.2:c.N/AIntron Variant
ZHX3 transcript variant X4XM_011528704.2:c.N/AIntron Variant
ZHX3 transcript variant X7XM_011528705.2:c.N/AIntron Variant
ZHX3 transcript variant X9XM_011528706.2:c.N/AIntron Variant
ZHX3 transcript variant X8XM_011528707.2:c.N/AIntron Variant
ZHX3 transcript variant X10XM_011528708.2:c.N/AIntron Variant
ZHX3 transcript variant X6XM_011528709.2:c.N/AIntron Variant
ZHX3 transcript variant X12XM_011528711.2:c.N/AIntron Variant
ZHX3 transcript variant X10XM_011528713.2:c.N/AIntron Variant
ZHX3 transcript variant X14XM_011528714.2:c.N/AIntron Variant
ZHX3 transcript variant X13XM_011528717.2:c.N/AIntron Variant
ZHX3 transcript variant X14XM_011528718.2:c.N/AIntron Variant
ZHX3 transcript variant X21XM_011528720.1:c.N/AIntron Variant
ZHX3 transcript variant X2XM_017027736.1:c.N/AIntron Variant
ZHX3 transcript variant X19XM_017027737.1:c.N/AIntron Variant
ZHX3 transcript variant X21XM_017027738.1:c.N/AIntron Variant
ZHX3 transcript variant X16XM_006723749.3:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.745C=0.255
1000GenomesAmericanSub694T=0.790C=0.210
1000GenomesEast AsianSub1008T=0.749C=0.251
1000GenomesEuropeSub1006T=0.822C=0.178
1000GenomesGlobalStudy-wide5008T=0.760C=0.240
1000GenomesSouth AsianSub978T=0.710C=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.790C=0.210
The Genome Aggregation DatabaseAfricanSub8684T=0.770C=0.230
The Genome Aggregation DatabaseAmericanSub838T=0.850C=0.150
The Genome Aggregation DatabaseEast AsianSub1618T=0.759C=0.241
The Genome Aggregation DatabaseEuropeSub18456T=0.799C=0.200
The Genome Aggregation DatabaseGlobalStudy-wide29898T=0.790C=0.209
The Genome Aggregation DatabaseOtherSub302T=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.788C=0.211
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.784C=0.216
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs61297840.000695nicotine smoking19268276

eQTL of rs6129784 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6129784 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr203984179339841938E067-43591
chr203984198939842412E067-43117
chr203984267039842714E067-42815
chr203984280239842852E067-42677
chr203984308039843140E067-42389
chr203985035439850506E067-35023
chr203985060039850822E067-34707
chr203985085839852097E067-33432
chr203985288139853303E067-32226
chr203985360739853654E067-31875
chr203985378439853997E067-31532
chr203985661139856733E067-28796
chr203985712139857208E067-28321
chr203985761039857673E067-27856
chr203985767739857745E067-27784
chr203985796939858204E067-27325
chr203985859739858683E067-26846
chr203985891639859122E067-26407
chr203985925339859297E067-26232
chr203985941539859486E067-26043
chr203985991539860084E067-25445
chr203986058239860642E067-24887
chr203986067239861394E067-24135
chr203986150339863829E067-21700
chr203986945939869547E067-15982
chr203986978539869835E067-15694
chr203987095939871077E067-14452
chr203987115239871666E067-13863
chr203987341239873462E067-12067
chr203987368039873848E067-11681
chr203987394639874364E067-11165
chr203987449539874611E067-10918
chr203987473139874837E067-10692
chr203987497339875070E067-10459
chr203987578039875885E067-9644
chr203987596139876015E067-9514
chr203987606239876166E067-9363
chr203987623539876477E067-9052
chr203987648739876685E067-8844
chr203987673639876895E067-8634
chr203987690039879042E067-6487
chr203987907539879129E067-6400
chr203988944639889664E0673917
chr203988972539889794E0674196
chr203988988939889939E0674360
chr203988997939890166E0674450
chr203989018839890302E0674659
chr203989036339890452E0674834
chr203989062839890871E0675099
chr203989093139891344E0675402
chr203989600839896179E06710479
chr203989764939897820E06712120
chr203989789539898261E06712366
chr203990289139902935E06717362
chr203990348639903530E06717957
chr203990381639903870E06718287
chr203990395039904058E06718421
chr203990411739904401E06718588
chr203990442639904539E06718897
chr203990462539904675E06719096
chr203990470539904825E06719176
chr203990761639907679E06722087
chr203990775539907889E06722226
chr203990802939908182E06722500
chr203990832939908412E06722800
chr203990848639908799E06722957
chr203990883439908884E06723305
chr203990891939908970E06723390
chr203991898839919032E06733459
chr203991914339919196E06733614
chr203991931539919594E06733786
chr203991961539919813E06734086
chr203991993739920016E06734408
chr203992168839921779E06736159
chr203992197939922580E06736450
chr203992262039922807E06737091
chr203992299139923069E06737462
chr203992666939926741E06741140
chr203992685239926913E06741323
chr203992730339927357E06741774
chr203992919239929242E06743663
chr203992946439929540E06743935
chr203992959139929753E06744062
chr203993194739932002E06746418
chr203993272439932857E06747195
chr203993289439933100E06747365
chr203993322339933656E06747694
chr203984039839840478E068-45051
chr203984056739840617E068-44912
chr203984151239841589E068-43940
chr203984179339841938E068-43591
chr203984198939842412E068-43117
chr203984267039842714E068-42815
chr203984280239842852E068-42677
chr203984308039843140E068-42389
chr203984835039848404E068-37125
chr203984842939848473E068-37056
chr203984848939848539E068-36990
chr203984974639849786E068-35743
chr203984985539849905E068-35624
chr203985002139850084E068-35445
chr203985010639850166E068-35363
chr203985035439850506E068-35023
chr203985060039850822E068-34707
chr203985085839852097E068-33432
chr203985288139853303E068-32226
chr203985360739853654E068-31875
chr203985378439853997E068-31532
chr203985712139857208E068-28321
chr203985761039857673E068-27856
chr203985767739857745E068-27784
chr203985796939858204E068-27325
chr203985859739858683E068-26846
chr203985891639859122E068-26407
chr203985925339859297E068-26232
chr203985941539859486E068-26043
chr203985991539860084E068-25445
chr203986058239860642E068-24887
chr203986067239861394E068-24135
chr203986150339863829E068-21700
chr203986816639868258E068-17271
chr203986834239868403E068-17126
chr203986945939869547E068-15982
chr203986978539869835E068-15694
chr203987095939871077E068-14452
chr203987115239871666E068-13863
chr203987289039872972E068-12557
chr203987297839873049E068-12480
chr203987341239873462E068-12067
chr203987368039873848E068-11681
chr203987394639874364E068-11165
chr203987449539874611E068-10918
chr203987473139874837E068-10692
chr203987497339875070E068-10459
chr203987578039875885E068-9644
chr203987596139876015E068-9514
chr203987606239876166E068-9363
chr203987623539876477E068-9052
chr203987648739876685E068-8844
chr203987673639876895E068-8634
chr203987690039879042E068-6487
chr203988944639889664E0683917
chr203988972539889794E0684196
chr203988988939889939E0684360
chr203988997939890166E0684450
chr203989018839890302E0684659
chr203989036339890452E0684834
chr203989062839890871E0685099
chr203989093139891344E0685402
chr203989600839896179E06810479
chr203989764939897820E06812120
chr203989789539898261E06812366
chr203990066639900752E06815137
chr203990083239900953E06815303
chr203990105339901150E06815524
chr203990126339901313E06815734
chr203990135339901403E06815824
chr203990141439901511E06815885
chr203990289139902935E06817362
chr203990348639903530E06817957
chr203990381639903870E06818287
chr203990395039904058E06818421
chr203990411739904401E06818588
chr203990442639904539E06818897
chr203990462539904675E06819096
chr203990470539904825E06819176
chr203990490839905488E06819379
chr203990761639907679E06822087
chr203990775539907889E06822226
chr203990802939908182E06822500
chr203990832939908412E06822800
chr203990848639908799E06822957
chr203990883439908884E06823305
chr203990891939908970E06823390
chr203991289239912952E06827363
chr203991300339913062E06827474
chr203991332239913377E06827793
chr203991814539918240E06832616
chr203991898839919032E06833459
chr203991914339919196E06833614
chr203991931539919594E06833786
chr203991961539919813E06834086
chr203991993739920016E06834408
chr203992135939921452E06835830
chr203992168839921779E06836159
chr203992197939922580E06836450
chr203992262039922807E06837091
chr203992299139923069E06837462
chr203992666939926741E06841140
chr203992685239926913E06841323
chr203992730339927357E06841774
chr203992844039928490E06842911
chr203992869839928812E06843169
chr203992886639928920E06843337
chr203992919239929242E06843663
chr203992946439929540E06843935
chr203992959139929753E06844062
chr203993194739932002E06846418
chr203993272439932857E06847195
chr203993289439933100E06847365
chr203993322339933656E06847694
chr203993525439935330E06849725
chr203984151239841589E069-43940
chr203984179339841938E069-43591
chr203984198939842412E069-43117
chr203984267039842714E069-42815
chr203984280239842852E069-42677
chr203984308039843140E069-42389
chr203984328239843733E069-41796
chr203984623439846301E069-39228
chr203984645939846529E069-39000
chr203984974639849786E069-35743
chr203984985539849905E069-35624
chr203985002139850084E069-35445
chr203985010639850166E069-35363
chr203985035439850506E069-35023
chr203985060039850822E069-34707
chr203985085839852097E069-33432
chr203985288139853303E069-32226
chr203985360739853654E069-31875
chr203985378439853997E069-31532
chr203985712139857208E069-28321
chr203985761039857673E069-27856
chr203985767739857745E069-27784
chr203985796939858204E069-27325
chr203985859739858683E069-26846
chr203985891639859122E069-26407
chr203985925339859297E069-26232
chr203985941539859486E069-26043
chr203985991539860084E069-25445
chr203986058239860642E069-24887
chr203986067239861394E069-24135
chr203986150339863829E069-21700
chr203986945939869547E069-15982
chr203986978539869835E069-15694
chr203987056539870615E069-14914
chr203987095939871077E069-14452
chr203987115239871666E069-13863
chr203987203639872102E069-13427
chr203987289039872972E069-12557
chr203987297839873049E069-12480
chr203987341239873462E069-12067
chr203987368039873848E069-11681
chr203987394639874364E069-11165
chr203987449539874611E069-10918
chr203987473139874837E069-10692
chr203987497339875070E069-10459
chr203987578039875885E069-9644
chr203987596139876015E069-9514
chr203987606239876166E069-9363
chr203987623539876477E069-9052
chr203987648739876685E069-8844
chr203987673639876895E069-8634
chr203987690039879042E069-6487
chr203987907539879129E069-6400
chr203987929039879344E069-6185
chr203987938039879455E069-6074
chr203988944639889664E0693917
chr203988972539889794E0694196
chr203988988939889939E0694360
chr203988997939890166E0694450
chr203989018839890302E0694659
chr203989036339890452E0694834
chr203989600839896179E06910479
chr203989764939897820E06912120
chr203989789539898261E06912366
chr203990126339901313E06915734
chr203990411739904401E06918588
chr203990442639904539E06918897
chr203990462539904675E06919096
chr203990470539904825E06919176
chr203990761639907679E06922087
chr203990775539907889E06922226
chr203990802939908182E06922500
chr203990832939908412E06922800
chr203990848639908799E06922957
chr203990883439908884E06923305
chr203990891939908970E06923390
chr203991898839919032E06933459
chr203991914339919196E06933614
chr203991931539919594E06933786
chr203991961539919813E06934086
chr203991993739920016E06934408
chr203992120339921269E06935674
chr203992135939921452E06935830
chr203992168839921779E06936159
chr203992197939922580E06936450
chr203992262039922807E06937091
chr203992869839928812E06943169
chr203992886639928920E06943337
chr203992919239929242E06943663
chr203992946439929540E06943935
chr203992959139929753E06944062
chr203993272439932857E06947195
chr203993289439933100E06947365
chr203993322339933656E06947694
chr203993525439935330E06949725
chr203984179339841938E070-43591
chr203984198939842412E070-43117
chr203984267039842714E070-42815
chr203984280239842852E070-42677
chr203984308039843140E070-42389
chr203984328239843733E070-41796
chr203985035439850506E070-35023
chr203985060039850822E070-34707
chr203985085839852097E070-33432
chr203985288139853303E070-32226
chr203986058239860642E070-24887
chr203986067239861394E070-24135
chr203986150339863829E070-21700
chr203987341239873462E070-12067
chr203987368039873848E070-11681
chr203987394639874364E070-11165
chr203987449539874611E070-10918
chr203987473139874837E070-10692
chr203987690039879042E070-6487
chr203984151239841589E071-43940
chr203984179339841938E071-43591
chr203984198939842412E071-43117
chr203984267039842714E071-42815
chr203984280239842852E071-42677
chr203984308039843140E071-42389
chr203984328239843733E071-41796
chr203984835039848404E071-37125
chr203984842939848473E071-37056
chr203984848939848539E071-36990
chr203984974639849786E071-35743
chr203984985539849905E071-35624
chr203985002139850084E071-35445
chr203985010639850166E071-35363
chr203985035439850506E071-35023
chr203985085839852097E071-33432
chr203985288139853303E071-32226
chr203985360739853654E071-31875
chr203985378439853997E071-31532
chr203985712139857208E071-28321
chr203985761039857673E071-27856
chr203985767739857745E071-27784
chr203985796939858204E071-27325
chr203985859739858683E071-26846
chr203985891639859122E071-26407
chr203985925339859297E071-26232
chr203985941539859486E071-26043
chr203985991539860084E071-25445
chr203986058239860642E071-24887
chr203986067239861394E071-24135
chr203986150339863829E071-21700
chr203986945939869547E071-15982
chr203986978539869835E071-15694
chr203987095939871077E071-14452
chr203987115239871666E071-13863
chr203987289039872972E071-12557
chr203987297839873049E071-12480
chr203987341239873462E071-12067
chr203987368039873848E071-11681
chr203987394639874364E071-11165
chr203987449539874611E071-10918
chr203987473139874837E071-10692
chr203987497339875070E071-10459
chr203987578039875885E071-9644
chr203987596139876015E071-9514
chr203987606239876166E071-9363
chr203987623539876477E071-9052
chr203987648739876685E071-8844
chr203987673639876895E071-8634
chr203987690039879042E071-6487
chr203988944639889664E0713917
chr203988972539889794E0714196
chr203988988939889939E0714360
chr203988997939890166E0714450
chr203989018839890302E0714659
chr203989036339890452E0714834
chr203989062839890871E0715099
chr203989093139891344E0715402
chr203989764939897820E07112120
chr203989789539898261E07112366
chr203990395039904058E07118421
chr203990411739904401E07118588
chr203990442639904539E07118897
chr203990462539904675E07119096
chr203990470539904825E07119176
chr203990490839905488E07119379
chr203990761639907679E07122087
chr203990775539907889E07122226
chr203990802939908182E07122500
chr203990832939908412E07122800
chr203990848639908799E07122957
chr203990883439908884E07123305
chr203990891939908970E07123390
chr203991814539918240E07132616
chr203991898839919032E07133459
chr203991914339919196E07133614
chr203991931539919594E07133786
chr203991961539919813E07134086
chr203991993739920016E07134408
chr203992120339921269E07135674
chr203992135939921452E07135830
chr203992168839921779E07136159
chr203992197939922580E07136450
chr203992262039922807E07137091
chr203992685239926913E07141323
chr203992869839928812E07143169
chr203992886639928920E07143337
chr203992919239929242E07143663
chr203992946439929540E07143935
chr203992959139929753E07144062
chr203993194739932002E07146418
chr203993272439932857E07147195
chr203993289439933100E07147365
chr203993322339933656E07147694
chr203984151239841589E072-43940
chr203984179339841938E072-43591
chr203984198939842412E072-43117
chr203984267039842714E072-42815
chr203984280239842852E072-42677
chr203984308039843140E072-42389
chr203984974639849786E072-35743
chr203984985539849905E072-35624
chr203985002139850084E072-35445
chr203985010639850166E072-35363
chr203985035439850506E072-35023
chr203985085839852097E072-33432
chr203985288139853303E072-32226
chr203985360739853654E072-31875
chr203985378439853997E072-31532
chr203985712139857208E072-28321
chr203985761039857673E072-27856
chr203985767739857745E072-27784
chr203985796939858204E072-27325
chr203985859739858683E072-26846
chr203985891639859122E072-26407
chr203985925339859297E072-26232
chr203985941539859486E072-26043
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