rs632582

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0455 (13255/29118,TOPMED)
A=0482 (12905/26724,GnomAD)
A=0466 (2334/5008,1000G)
A=0380 (1466/3854,ALSPAC)
A=0393 (1457/3708,TWINSUK)
chr6:107853969 (GRCh38.p7) (6q21)
AD
GWASdb2
1   publication(s)
See rs on genome
53 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.107853969G>A
GRCh37.p13 chr 6NC_000006.11:g.108175173G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.193A=0.807
1000GenomesAmericanSub694G=0.670A=0.330
1000GenomesEast AsianSub1008G=0.648A=0.352
1000GenomesEuropeSub1006G=0.617A=0.383
1000GenomesGlobalStudy-wide5008G=0.534A=0.466
1000GenomesSouth AsianSub978G=0.690A=0.310
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.620A=0.380
The Genome Aggregation DatabaseAfricanSub7990G=0.257A=0.743
The Genome Aggregation DatabaseAmericanSub702G=0.740A=0.260
The Genome Aggregation DatabaseEast AsianSub1580G=0.684A=0.316
The Genome Aggregation DatabaseEuropeSub16158G=0.617A=0.382
The Genome Aggregation DatabaseGlobalStudy-wide26724G=0.517A=0.482
The Genome Aggregation DatabaseOtherSub294G=0.610A=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.455A=0.544
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.607A=0.393
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs6325820.000974alcohol dependence21314694

eQTL of rs632582 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs632582 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6108186285108186466E06711112
chr6108201180108202145E06726007
chr6108203065108203433E06727892
chr6108203465108203553E06728292
chr6108203065108203433E06827892
chr6108203465108203553E06828292
chr6108200963108201017E06925790
chr6108201180108202145E06926007
chr6108202820108202890E06927647
chr6108202966108203020E06927793
chr6108203065108203433E06927892
chr6108203465108203553E06928292
chr6108128029108128176E070-46997
chr6108128405108128642E070-46531
chr6108128971108129036E070-46137
chr6108129285108129384E070-45789
chr6108141025108141165E070-34008
chr6108146342108146540E070-28633
chr6108185462108185544E07010289
chr6108185552108185690E07010379
chr6108186285108186466E07011112
chr6108201180108202145E07126007
chr6108202820108202890E07127647
chr6108202966108203020E07127793
chr6108203065108203433E07127892
chr6108203465108203553E07128292
chr6108203855108203932E07128682
chr6108188169108188706E07212996
chr6108188169108188706E07412996
chr6108201180108202145E07426007
chr6108202820108202890E07427647
chr6108202966108203020E07427793
chr6108203065108203433E07427892
chr6108203465108203553E07428292
chr6108125300108125461E081-49712
chr6108125507108125557E081-49616
chr6108128029108128176E081-46997
chr6108128405108128642E081-46531
chr6108128971108129036E081-46137
chr6108129285108129384E081-45789
chr6108146342108146540E081-28633
chr6108186285108186466E08111112
chr6108201180108202145E08126007
chr6108128029108128176E082-46997
chr6108128405108128642E082-46531
chr6108128971108129036E082-46137
chr6108129285108129384E082-45789
chr6108141025108141165E082-34008
chr6108200963108201017E08225790
chr6108201180108202145E08226007
chr6108202820108202890E08227647
chr6108202966108203020E08227793
chr6108203065108203433E08227892









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6108169122108170223E067-4950
chr6108169122108170223E068-4950
chr6108169122108170223E069-4950
chr6108169122108170223E070-4950
chr6108169122108170223E072-4950
chr6108169122108170223E073-4950
chr6108169122108170223E074-4950
chr6108169122108170223E082-4950