rs633687

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0221 (6641/29924,GnomAD)
G==0214 (6234/29118,TOPMED)
G==0174 (873/5008,1000G)
G==0243 (937/3854,ALSPAC)
G==0249 (925/3708,TWINSUK)
chr11:88202856 (GRCh38.p7) (11q14.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.88202856G>A
GRCh37.p13 chr 11NC_000011.9:g.87936024G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.097A=0.903
1000GenomesAmericanSub694G=0.240A=0.760
1000GenomesEast AsianSub1008G=0.143A=0.857
1000GenomesEuropeSub1006G=0.256A=0.744
1000GenomesGlobalStudy-wide5008G=0.174A=0.826
1000GenomesSouth AsianSub978G=0.180A=0.820
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.243A=0.757
The Genome Aggregation DatabaseAfricanSub8718G=0.121A=0.879
The Genome Aggregation DatabaseAmericanSub832G=0.270A=0.730
The Genome Aggregation DatabaseEast AsianSub1604G=0.124A=0.876
The Genome Aggregation DatabaseEuropeSub18468G=0.275A=0.724
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.221A=0.778
The Genome Aggregation DatabaseOtherSub302G=0.240A=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.214A=0.785
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.249A=0.751
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs6336876.44E-05alcohol dependence21703634

eQTL of rs633687 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs633687 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr118790754987909350E067-26674
chr118790754987909350E068-26674
chr118790754987909350E069-26674
chr118790754987909350E070-26674
chr118790754987909350E071-26674
chr118790754987909350E082-26674