rs6415652

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0291 (8712/29916,GnomAD)
G==0276 (8041/29118,TOPMED)
G==0328 (1645/5008,1000G)
G==0340 (1310/3854,ALSPAC)
G==0332 (1232/3708,TWINSUK)
chr8:81790022 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
68 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81790022G>A
GRCh37.p13 chr 8NC_000008.10:g.82702257G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.143A=0.857
1000GenomesAmericanSub694G=0.350A=0.650
1000GenomesEast AsianSub1008G=0.553A=0.447
1000GenomesEuropeSub1006G=0.341A=0.659
1000GenomesGlobalStudy-wide5008G=0.328A=0.672
1000GenomesSouth AsianSub978G=0.320A=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.340A=0.660
The Genome Aggregation DatabaseAfricanSub8722G=0.168A=0.832
The Genome Aggregation DatabaseAmericanSub838G=0.320A=0.680
The Genome Aggregation DatabaseEast AsianSub1610G=0.580A=0.420
The Genome Aggregation DatabaseEuropeSub18446G=0.321A=0.678
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.291A=0.708
The Genome Aggregation DatabaseOtherSub300G=0.380A=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.276A=0.723
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.332A=0.668
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs64156523.66E-05alcohol consumption23743675

eQTL of rs6415652 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6415652 in Fetal Brain

Probe ID Position Gene beta p-value
cg17211192chr8:82754475SNX160.06175045250404923.4143e-23
cg23324259chr8:82754387SNX160.01876774609066619.8973e-16
cg27398817chr8:82754497SNX160.03799498698989571.0755e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88272692182727044E06724664
chr88272708482727145E06724827
chr88272739782727713E06725140
chr88275141582751459E06749158
chr88275155182751632E06749294
chr88275169382751743E06749436
chr88275176982751905E06749512
chr88275192082751978E06749663
chr88275205182752101E06749794
chr88274913582749745E06846878
chr88275040382750493E06848146
chr88275055782750622E06848300
chr88275073382750913E06848476
chr88275118682751259E06848929
chr88275141582751459E06849158
chr88275155182751632E06849294
chr88275169382751743E06849436
chr88275205182752101E06949794
chr88270876682709232E0706509
chr88270927582709325E0707018
chr88270935482709440E0707097
chr88273635982736422E07034102
chr88273760682737656E07035349
chr88273770482737783E07035447
chr88274913582749745E07046878
chr88272692182727044E07124664
chr88272739782727713E07125140
chr88275040382750493E07148146
chr88275055782750622E07148300
chr88275073382750913E07148476
chr88275176982751905E07149512
chr88275192082751978E07149663
chr88275205182752101E07149794
chr88269268482693377E072-8880
chr88272629482726439E07224037
chr88272692182727044E07224664
chr88272708482727145E07224827
chr88272739782727713E07225140
chr88272739782727713E07325140
chr88272692182727044E07424664
chr88275040382750493E07448146
chr88275055782750622E07448300
chr88275073382750913E07448476
chr88275118682751259E07448929
chr88275141582751459E07449158
chr88275155182751632E07449294
chr88275169382751743E07449436
chr88275176982751905E07449512
chr88275192082751978E07449663
chr88275205182752101E07449794
chr88269268482693377E081-8880
chr88274894182748991E08146684
chr88275118682751259E08148929
chr88275141582751459E08149158
chr88275155182751632E08149294
chr88275169382751743E08149436
chr88275176982751905E08149512
chr88275192082751978E08149663
chr88275205182752101E08149794
chr88269939382699447E082-2810
chr88269957982699654E082-2603
chr88274913582749745E08246878
chr88274982582749873E08247568
chr88275155182751632E08249294
chr88275169382751743E08249436
chr88275176982751905E08249512
chr88275192082751978E08249663
chr88275205182752101E08249794