rs6415653

Homo sapiens
A>C / A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0290 (8677/29856,GnomAD)
A==0328 (1645/5008,1000G)
A==0341 (1314/3854,ALSPAC)
A==0333 (1233/3708,TWINSUK)
chr8:81790301 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81790301A>C
GRCh38.p7 chr 8NC_000008.11:g.81790301A>G
GRCh37.p13 chr 8NC_000008.10:g.82702536A>C
GRCh37.p13 chr 8NC_000008.10:g.82702536A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.143G=0.857
1000GenomesAmericanSub694A=0.350G=0.650
1000GenomesEast AsianSub1008A=0.553G=0.447
1000GenomesEuropeSub1006A=0.341G=0.659
1000GenomesGlobalStudy-wide5008A=0.328G=0.672
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.341G=0.659
The Genome Aggregation DatabaseAfricanSub8710A=0.168G=0.832
The Genome Aggregation DatabaseAmericanSub836A=0.320G=0.680
The Genome Aggregation DatabaseEast AsianSub1608A=0.578G=0.422
The Genome Aggregation DatabaseEuropeSub18400A=0.320G=0.679
The Genome Aggregation DatabaseGlobalStudy-wide29856A=0.290G=0.709
The Genome Aggregation DatabaseOtherSub302A=0.380G=0.620
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.333G=0.667
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs64156533.42E-05alcohol consumption23743675

eQTL of rs6415653 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6415653 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8101773554101775046E068-33919
chr8101847470101848214E06838505
chr8101762717101763214E071-45751
chr8101764400101764498E071-44467
chr8101764560101764751E071-44214
chr8101764770101764823E071-44142
chr8101803597101803661E072-5304
chr8101803758101804338E074-4627
chr8101804391101804510E074-4455
chr8101847470101848214E07438505
chr8101848259101848339E07439294
chr8101775773101775823E081-33142
chr8101775832101775882E081-33083
chr8101775951101776079E081-32886
chr8101803597101803661E081-5304
chr8101803758101804338E081-4627
chr8101804391101804510E081-4455
chr8101851627101851825E08142662
chr8101851845101851917E08142880
chr8101775334101775644E082-33321