rs6424380

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
T==0084 (2527/29946,GnomAD)
T==0122 (3566/29118,TOPMED)
T==0096 (481/5008,1000G)
T==0001 (4/3854,ALSPAC)
T==0001 (4/3708,TWINSUK)
chr1:145863686 (GRCh38.p7) (1q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.145863686G>A
GRCh37.p13 chr 1 fix patch HG1287_PATCHNW_003871055.3:g.2679099G>A
GRCh37.p13 chr 1NC_000001.10:g.145571398T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.318G==0.682
1000GenomesAmericanSub694A=0.020G==0.980
1000GenomesEast AsianSub1008A=0.017G==0.983
1000GenomesEuropeSub1006A=0.001G==0.999
1000GenomesGlobalStudy-wide5008A=0.096G==0.904
1000GenomesSouth AsianSub978A=0.030G==0.970
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.001G==0.999
The Genome Aggregation DatabaseAfricanSub8702A=0.283G==0.717
The Genome Aggregation DatabaseAmericanSub838A=0.020G==0.980
The Genome Aggregation DatabaseEast AsianSub1622A=0.025G==0.975
The Genome Aggregation DatabaseEuropeSub18482A=0.000G==0.999
The Genome Aggregation DatabaseGlobalStudy-wide29946A=0.084G==0.915
The Genome Aggregation DatabaseOtherSub302A=0.000G==1.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.122G==0.877
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.001G==0.999
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs64243800.000125alcohol dependence21314694

eQTL of rs6424380 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6424380 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr126947112694903E07015612
chr127233902723444E07044291
chr126947112694903E07215612
chr126947112694903E08115612
chr126947112694903E08215612