rs6429835

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0395 (11779/29760,GnomAD)
T=0356 (10379/29118,TOPMED)
T=0348 (1745/5008,1000G)
T=0442 (1702/3854,ALSPAC)
T=0426 (1581/3708,TWINSUK)
chr1:82766183 (GRCh38.p7) (1p31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.82766183C>T
GRCh37.p13 chr 1NC_000001.10:g.83231866C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.682T=0.318
1000GenomesAmericanSub694C=0.660T=0.340
1000GenomesEast AsianSub1008C=0.665T=0.335
1000GenomesEuropeSub1006C=0.618T=0.382
1000GenomesGlobalStudy-wide5008C=0.652T=0.348
1000GenomesSouth AsianSub978C=0.620T=0.380
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.558T=0.442
The Genome Aggregation DatabaseAfricanSub8684C=0.683T=0.317
The Genome Aggregation DatabaseAmericanSub834C=0.680T=0.320
The Genome Aggregation DatabaseEast AsianSub1550C=0.670T=0.330
The Genome Aggregation DatabaseEuropeSub18392C=0.557T=0.443
The Genome Aggregation DatabaseGlobalStudy-wide29760C=0.604T=0.395
The Genome Aggregation DatabaseOtherSub300C=0.690T=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.643T=0.356
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.574T=0.426
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs64298353.79E-05alcohol dependence21703634

eQTL of rs6429835 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6429835 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18325230883252362E06820442
chr18325294683253021E06921080
chr18327919783279382E07047331
chr18327919783279382E08147331
chr18325294683253021E08221080