rs6432628

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0205 (6151/29932,GnomAD)
T=0212 (6196/29118,TOPMED)
T=0187 (935/5008,1000G)
T=0210 (809/3854,ALSPAC)
T=0204 (755/3708,TWINSUK)
chr2:160538677 (GRCh38.p7) (2q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.160538677C>T
GRCh37.p13 chr 2NC_000002.11:g.161395188C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.822T=0.178
1000GenomesAmericanSub694C=0.620T=0.380
1000GenomesEast AsianSub1008C=0.979T=0.021
1000GenomesEuropeSub1006C=0.780T=0.220
1000GenomesGlobalStudy-wide5008C=0.813T=0.187
1000GenomesSouth AsianSub978C=0.800T=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.790T=0.210
The Genome Aggregation DatabaseAfricanSub8700C=0.795T=0.205
The Genome Aggregation DatabaseAmericanSub836C=0.620T=0.380
The Genome Aggregation DatabaseEast AsianSub1622C=0.975T=0.025
The Genome Aggregation DatabaseEuropeSub18472C=0.787T=0.212
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.794T=0.205
The Genome Aggregation DatabaseOtherSub302C=0.710T=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.787T=0.212
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.796T=0.204
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs64326280.000091alcohol dependence20201924
rs64326280.0000913alcoholismpha002892

eQTL of rs6432628 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6432628 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2161348112161351258E067-43930
chr2161347524161347858E068-47330
chr2161347912161348070E068-47118
chr2161348112161351258E068-43930
chr2161348112161351258E069-43930
chr2161348112161351258E071-43930
chr2161348112161351258E072-43930
chr2161347912161348070E073-47118
chr2161348112161351258E073-43930
chr2161348112161351258E074-43930
chr2161348112161351258E082-43930